Protein Alignment MYC and CBF1

DIOPT Version :9

• Sequence 1: NP_002458.2
• Gene: MYC / 4609
• HGNCID: 7553
• Length: 454
• Species: Homo sapiens
• Sequence 2: NP_012594.1
• Gene: CBF1 / 853523
• SGDID: S000003821
• Length: 351
• Species: Saccharomyces cerevisiae
• Alignment Length: 249
• Identity: 49/249 - (19%)
• Similarity: 86/249 - (34%)
• Gaps: 96/249 - (38%)

Human   213 PLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEI 277
            |.|:...|.:  |.:....||     :.||:.|......||..|:..|        |.|:|:|:.
Yeast   139 PSNEGVKPNT--SLEGMTSSP-----MESTQQSKNDMLIPLAEHDRGP--------EHQQDDEDN 188

Human   278 DVVSVEKRQ----APGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAK 338
            |...::.::    .||:|
Yeast   189 DDADIDLKKDISMQPGRR----------------------------------------------- 206

Human   339 RVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNE 403
                           .||.|:..::|..:..::.:|..:||:||..:..:...|.|.:|..|::
Yeast   207 ---------------GRKPTTLATTDEWKKQRKDSHKEVERRRRENINTAINVLSDLLPVRESS- 255

Human   404 KAPKVVILKKATAYILSVQAEE---------QKLISEEDL--LRKRREQLKHKL 446
               |..||..|..||..::..:         |||:||::.  |....|:|:.:|
Yeast   256 ---KAAILACAAEYIQKLKETDEANIEKWTLQKLLSEQNASQLASANEKLQEEL 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYC	NP_002458.2	Myc_N	21..360	CDD:279405	24/150 (16%)
		HLH	370..426	CDD:238036	15/64 (23%)
		Myc-LZ	423..453	CDD:280500	9/35 (26%)
CBF1	NP_012594.1	HLH	220..272	CDD:238036	15/55 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910