Protein Alignment MYC and RTG3

DIOPT Version :9

• Sequence 1: NP_002458.2
• Gene: MYC / 4609
• HGNCID: 7553
• Length: 454
• Species: Homo sapiens
• Sequence 2: NP_009447.1
• Gene: RTG3 / 852171
• SGDID: S000000199
• Length: 486
• Species: Saccharomyces cerevisiae
• Alignment Length: 333
• Identity: 73/333 - (21%)
• Similarity: 111/333 - (33%)
• Gaps: 90/333 - (27%)

Human   170 ARKDSGSPNPARGHSVCSTSSLYLQD-----------------------LSAAASECIDPSV--V 209
            ||.:|.:|..:..:....:.|.||.|                       |.::.|...|..|  .
Yeast    83 ARSNSQTPTASTIYEEAESQSSYLDDMFRTSQGGRPVTQNSISSIGQGPLRSSYSMAYDSPVDRA 147

Human   210 FPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDE 274
            ...||......|:....|......:.|::.:.|:.........:.....||.|.||..   ..:.
Yeast   148 MNTPLQQQEGLKAELPHDFLFQHGTDDTMYNLTDDLSSSLSSSINSDMMTPNTYSSSF---SYNP 209

Human   275 EEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKR 339
            :.:...||....:|..||.|.|..||....             |:.:|.....|.||.
Yeast   210 QSLGPASVSSTYSPKVRSPSSSFRAGSFLS-------------SSFRHGSINTPRTRH------- 254

Human   340 VKLDSVRVLRQISNNR----------KCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRD 394
                     ..||:|.          |.....:||.:...||..||.:||:||..:|:....|..
Yeast   255 ---------TSISSNMTENIGPGSVPKILGGLTSDEKLRRKREFHNAVERRRRELIKQKIKELGQ 310

Human   395 QIP-------ELENNEKAPKVVILKKATAY------ILSVQAEEQKLISEEDLLRKRREQLKHKL 446
            .:|       :|....|..|.:||.:...|      ||.:||.::|.     ||.|.:|     |
Yeast   311 LVPPSLLNYDDLGKQIKPNKGIILDRTVEYLQYLAEILEIQARKKKA-----LLAKIKE-----L 365

Human   447 EQLRNSCA 454
            |:.::|.|
Yeast   366 EEKKSSVA 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYC	NP_002458.2	Myc_N	21..360	CDD:279405	41/224 (18%)
		HLH	370..426	CDD:238036	21/68 (31%)
		Myc-LZ	423..453	CDD:280500	8/29 (28%)
RTG3	NP_009447.1	bHLHzip_USF_MITF	289..349	CDD:381393	16/59 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910