Protein Alignment MYC and Myc

DIOPT Version :9

• Sequence 1: NP_002458.2
• Gene: MYC / 4609
• HGNCID: 7553
• Length: 454
• Species: Homo sapiens
• Sequence 2: NP_036735.2
• Gene: Myc / 24577
• RGDID: 3130
• Length: 453
• Species: Rattus norvegicus
• Alignment Length: 455
• Identity: 408/455 - (89%)
• Similarity: 423/455 - (92%)
• Gaps: 3/455 - (0%)

Human     1 MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIW 65
            |:|...||| ....||||||||.|||||||||||||||.||||||||.|||||||||||||||||
  Rat     1 MNFLWEVEN-PTVTTMPLNVSFANRNYDLDYDSVQPYFICDEEENFYHQQQQSELQPPAPSEDIW 64

Human    66 KKFELLPTPPLSPSRRSGLCSPSYVAV-TPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQS 129
            ||||||||||||||||||||||||||| |.||.|.|:|||||:|||||||||:||||||||||||
  Rat    65 KKFELLPTPPLSPSRRSGLCSPSYVAVATSFSPREDDDGGGGNFSTADQLEMMTELLGGDMVNQS 129

Human   130 FICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQ 194
            |||||||||||||||||||||||||||||||||||||||||||||.|.:||||||||||||||||
  Rat   130 FICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSTSLSPARGHSVCSTSSLYLQ 194

Human   195 DLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEET 259
            ||:||||||||||||||||||||||||||.|.||:|||.|||||||| ||||:.:||||||||||
  Rat   195 DLTAAASECIDPSVVFPYPLNDSSSPKSCTSSDSTAFSSSSDSLLSS-ESSPRATPEPLVLHEET 258

Human   260 PPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNY 324
            ||||||||||||:||||||||||||||.|.|||||||..:.||||||||||||||||||||||||
  Rat   259 PPTTSSDSEEEQDDEEEIDVVSVEKRQPPAKRSESGSSPSRGHSKPPHSPLVLKRCHVSTHQHNY 323

Human   325 AAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSF 389
            |||||||||||||||.||||.|||:||||||||:||||||||||.||||||||||||||||||||
  Rat   324 AAPPSTRKDYPAAKRAKLDSGRVLKQISNNRKCSSPRSSDTEENDKRRTHNVLERQRRNELKRSF 388

Human   390 FALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA 454
            ||||||||||||||||||||||||||||||||||:|.|||||:||||||||||||||||||||.|
  Rat   389 FALRDQIPELENNEKAPKVVILKKATAYILSVQADEHKLISEKDLLRKRREQLKHKLEQLRNSGA 453

Human   455  454
              Rat   454  453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYC	NP_002458.2	Myc_N	21..360	CDD:279405	306/339 (90%)
		HLH	370..426	CDD:238036	54/55 (98%)
		Myc-LZ	423..453	CDD:280500	26/29 (90%)
Myc	NP_036735.2	Myc_N	20..359	CDD:279405	306/339 (90%)
		HLH	366..425	CDD:238036	56/58 (97%)
		Myc-LZ	422..451	CDD:280500	25/28 (89%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	628	1.000	Domainoid score	I4446
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31092
Inparanoid	1	1.050	795	1.000	Inparanoid score	I7571
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG50300
OrthoDB	1	1.010	-	-		D132262at9347
OrthoFinder	1	1.000	-	-		FOG0006386
OrthoInspector	1	1.000	-	-		oto138044
orthoMCL	1	0.900	-	-		OOG6_115159
Panther	1	1.100	-	-	LDO	PTHR45851
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X7143
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	15.480