Protein Alignment MYC and hlh-10

DIOPT Version :9

• Sequence 1: NP_002458.2
• Gene: MYC / 4609
• HGNCID: 7553
• Length: 454
• Species: Homo sapiens
• Sequence 2: NP_505401.2
• Gene: hlh-10 / 191402
• WormBaseID: WBGene00001954
• Length: 202
• Species: Caenorhabditis elegans
• Alignment Length: 218
• Identity: 49/218 - (22%)
• Similarity: 81/218 - (37%)
• Gaps: 74/218 - (33%)

Human   237 SLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGG 301
            |:|.::.|.||       |.::.||         :.|.:|.|:|...|.:
 Worm    54 SMLEASASQPQ-------LTQDEPP---------ENDTKENDLVKQNKSE--------------- 87

Human   302 HSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTE 366
                             .:..|.:.|..|:.........|:|...|      .:.||
 Worm    88 -----------------VNDENESTPSPTQNSRRRTSTGKIDRRMV------GKMCT-------- 121

Human   367 ENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISE 431
               :|...|..||.|..:|.:.|..||..:| :|::.|..|:..||.|::||..:.|..|:..::
 Worm   122 ---RRYEANARERNRVQQLSKMFDQLRVCLP-IEDDAKISKLATLKVASSYIGYLGAILQENSND 182

Human   432 EDLLRKRREQLKHKLEQLRNSCA 454
            |:..:|   ||:.:||     ||
 Worm   183 EEEFKK---QLQVELE-----CA 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYC	NP_002458.2	Myc_N	21..360	CDD:279405	21/122 (17%)
		HLH	370..426	CDD:238036	19/55 (35%)
		Myc-LZ	423..453	CDD:280500	8/29 (28%)
hlh-10	NP_505401.2	bHLH_SF	121..179	CDD:381792	21/69 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910