Protein Alignment MYC and mdl-1

DIOPT Version :9

• Sequence 1: NP_002458.2
• Gene: MYC / 4609
• HGNCID: 7553
• Length: 454
• Species: Homo sapiens
• Sequence 2: NP_509136.1
• Gene: mdl-1 / 180942
• WormBaseID: WBGene00003163
• Length: 281
• Species: Caenorhabditis elegans
• Alignment Length: 229
• Identity: 50/229 - (21%)
• Similarity: 83/229 - (36%)
• Gaps: 75/229 - (32%)

Human   227 DSSAFSPSSDSL--LSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPG 289
            |..|...||..|  |:||.||| ||..|.:.              :..:|.|:..:...|.:...
 Worm    18 DIGALDISSLDLGALTSTSSSP-GSSSPAMF--------------DLSNESELRSLFCGKLKVDK 67

Human   290 KRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNN 354
            |:|...|                   :.||....|.:.|..||
 Worm    68 KQSSCAS-------------------NASTSSQPYCSSPPARK---------------------- 91

Human   355 RKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYIL 419
                |.:.|       |..||.||:.||..|:.....|:..:|.:.:..:...:.:|.:|..:|:
 Worm    92 ----SSKHS-------RTAHNELEKTRRANLRGCLETLKMLVPCVSDATRNTTLALLTRARDHII 145

Human   420 SVQ---AEEQKLISEEDLLRKRREQLKHKLEQLR 450
            .:|   |.:.|.:::   ||..:::|..:|.||:
 Worm   146 ELQDSNAAQMKKLND---LRDEQDELVAELAQLQ 176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYC	NP_002458.2	Myc_N	21..360	CDD:279405	26/134 (19%)
		HLH	370..426	CDD:238036	15/58 (26%)
		Myc-LZ	423..453	CDD:280500	8/28 (29%)
mdl-1	NP_509136.1	bHLHzip_Mad	97..172	CDD:381407	19/77 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910