Protein Alignment MYC and hlh-30

DIOPT Version :9

• Sequence 1: NP_002458.2
• Gene: MYC / 4609
• HGNCID: 7553
• Length: 454
• Species: Homo sapiens
• Sequence 2: NP_001023411.1
• Gene: hlh-30 / 177157
• WormBaseID: WBGene00020930
• Length: 524
• Species: Caenorhabditis elegans
• Alignment Length: 405
• Identity: 86/405 - (21%)
• Similarity: 141/405 - (34%)
• Gaps: 130/405 - (32%)

Human   100 DNDGGGGSFS----TADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLV 160
            ::.||||...    .|.|.....:........|.|.   |||.:..|.       |.|...|...
 Worm     6 NSPGGGGGLGLNNPRAQQPPGAQQQQQPQQAQQQFY---DDEPYQANA-------SQFRFGAGKS 60

Human   161 SEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCAS 225
            .|:       |:::|:..|....|:.|||:                    |:   .|:..:|...
 Worm    61 MEQ-------RRETGNLIPIAQRSMGSTST--------------------PF---GSAPTQSYFG 95

Human   226 QDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEE-------------------- 270
            ..||..:.||...:..|.....|:.:|   ...:||:..||....
 Worm    96 GGSSGAALSSPRKMQQTHQMLFGNIQP---PRGSPPSDGSDKIHRFGESPTPGGVGGVFGTELDD 157

Human   271 --------QEDEEEID-------VVSVEK-----RQAPGKRSESGSPSAGGHSKPPHSPLVLKRC 315
                    .||::.:.       .:..||     |..||..|.:||    |||   .||:.:...
 Worm   158 LIIDELMGMEDDQRMRPGATRPMTIGGEKTMSMARPIPGASSRAGS----GHS---GSPITIPNA 215

Human   316 HVSTHQH--NYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTE----ENVKRRTH 374
            ..:..:.  :.:||.|:           :|..:::..:||... .|...:|.|    :..|:..|
 Worm   216 MSNNFRQVVSSSAPTSS-----------IDIEKMIGAVSNGGG-NSGGDNDPEDYYRDRRKKDIH 268

Human   375 NVLERQRRNELKRSFFALRDQIPEL--------ENNEKAPKVVILKKATAYILSVQAE-EQKLIS 430
            |::||:||       :.:.|:|.||        ..:.|..|..|||.:..||..:|.: ||.:.:
 Worm   269 NMIERRRR-------YNINDRIKELGQMLPKNTSEDMKLNKGTILKASCDYIRVLQKDREQAMKT 326

Human   431 EEDLLRKRREQLKHK 445
            ::.  :|..|...||
 Worm   327 QQQ--QKSLESTAHK 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYC	NP_002458.2	Myc_N	21..360	CDD:279405	58/305 (19%)
		HLH	370..426	CDD:238036	19/64 (30%)
		Myc-LZ	423..453	CDD:280500	6/24 (25%)
hlh-30	NP_001023411.1	bHLHzip_MITF_like	260..328	CDD:381403	21/74 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910