Protein Alignment MYC and hlh-11

DIOPT Version :9

• Sequence 1: NP_002458.2
• Gene: MYC / 4609
• HGNCID: 7553
• Length: 454
• Species: Homo sapiens
• Sequence 2: NP_499129.2
• Gene: hlh-11 / 176360
• WormBaseID: WBGene00001955
• Length: 431
• Species: Caenorhabditis elegans
• Alignment Length: 247
• Identity: 56/247 - (22%)
• Similarity: 84/247 - (34%)
• Gaps: 91/247 - (36%)

Human   265 SDSEEE------------QEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHV 317
            |||.||            :||||.:               .||:.:.         |:.:...:.
 Worm     4 SDSAEEDQIIIDDGFDLTEEDEEMM---------------SSGTGAL---------PVTIADWNS 44

Human   318 STHQHNYAAPPSTRKDYPAAKRVKL------DSVRVLRQISN--------NRKCTSPR------- 361
            .|:..  .||||...   ||....|      :|:|.:...|.        ||..:.|.
 Worm    45 VTNAR--MAPPSIMS---AASAFDLTASGMQNSLRSVLPTSTIGHAPMLANRSLSQPAPLSPTSL 104

Human   362 SSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYI-------- 418
            ..|....::|:..|..||:|...:...|.|||..:|..| .||..|..||::....:
 Worm   105 DPDRRSRMRRQIANCNERRRMQSINAGFLALRALLPRKE-GEKLSKAAILQQTADMVHQLLGHKG 168

Human   419 --LSVQAEEQKLISEED---------------LL---RKRREQLKHKLEQLR 450
              :....|.:||..|||               :|   |..|:.|:.::.|||
 Worm   169 EDIPDGGEPKKLKLEEDHHDADHQAQIAHLQTILETERAARKALESQVIQLR 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYC	NP_002458.2	Myc_N	21..360	CDD:279405	25/120 (21%)
		HLH	370..426	CDD:238036	17/65 (26%)
		Myc-LZ	423..453	CDD:280500	13/46 (28%)
hlh-11	NP_499129.2	HLH	113..163	CDD:278439	16/50 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910