Protein Alignment MYC and mml-1

DIOPT Version :9

• Sequence 1: NP_002458.2
• Gene: MYC / 4609
• HGNCID: 7553
• Length: 454
• Species: Homo sapiens
• Sequence 2: NP_498631.2
• Gene: mml-1 / 176050
• WormBaseID: WBGene00003378
• Length: 1009
• Species: Caenorhabditis elegans
• Alignment Length: 505
• Identity: 116/505 - (22%)
• Similarity: 187/505 - (37%)
• Gaps: 129/505 - (25%)

Human    16 MPLNVSFTNRNYDLDYDSVQPYFYCDEEENF-----YQQQQQSEL--QP---PAPSEDIWKKFEL 70
            :|:..:.||::: |.:.|....:...::.||     :|...:..|  ||   |.||     :..|
 Worm   444 LPIRNTMTNQHH-LGHTSQHSPWNKQQQSNFLVSLPHQSHVERILNNQPPLVPPPS-----RSNL 502

Human    71 LPT-----------------------PPLSPSRRSGLCSPSYVAV-------TPFSLRGDNDGG- 104
            |||                       |.::|||...|.||...:|       ||..|.  |..|
 Worm   503 LPTQNDPYLPQFLQSTQPTPQPQSHDPMMAPSRSWWLDSPLTASVQSPLSVATPLPLA--NQTGP 565

Human   105 ----GGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLA 165
                |....:||.    ..|.||:.....|                  ..||.::....:|::|.
 Worm   566 QTPLGQLIGSADN----GFLFGGNNTPGGF------------------KMSGTTSGVPTLSQRLE 608

Human   166 SYQAARKDSGSPN----PAR------GHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSS- 219
            ....:|..:...|    |.|      ..:..:.|.|.:..||...:..::.|....:.:..|.:
 Worm   609 QPPISRTSTIFGNVENKPERIFTSLTSQNTPTPSPLDISSLSRLRTSSLNESWKMSHIVEGSPTY 673

Human   220 ---PKSCASQDSSAFSPSSDSLLSSTESSP-QGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVV 280
               ..|..::.|...|||:...:|...|.| |.|..|..:  .|||:.||     :..|:|..:.
 Worm   674 QAFAASVTTKPSILESPSTSGDISGPASVPVQASQHPPKI--ITPPSASS-----KRKEQEAAMA 731

Human   281 SVEKRQAP-------GKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAK 338
            .:..||..       ||.:......:|.|..|. :|..||  .|:..:....:.||
 Worm   732 PLVNRQQSCDVNLLNGKMAVKVEEKSGRHYLPT-TPTELK--EVTKEEPLLMSAPS--------- 784

Human   339 RVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPEL-ENN 402
                 ||:.:|:       .:|.|:...|..||..|...|:.||:.||..|..|.|.||:| ...
 Worm   785 -----SVKSMRR-------QAPDSTLHPEERKRILHLHAEQNRRSALKDGFDQLMDIIPDLYSGG 837

Human   403 EKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNS 452
            .|....|:|.|:..:|..:|||:.....:.|..:.:.|:|..|:..|:::
 Worm   838 VKPTNAVVLAKSADHIRRLQAEKWDKTQKIDEAKAKIEKLNQKITSLQSN 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYC	NP_002458.2	Myc_N	21..360	CDD:279405	85/405 (21%)
		HLH	370..426	CDD:238036	22/56 (39%)
		Myc-LZ	423..453	CDD:280500	7/30 (23%)
mml-1	NP_498631.2	HLH	801..859	CDD:238036	21/57 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910