DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS14 and Slc17a4

DIOPT Version :9

Sequence 1:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001258143.1	Gene:	Slc17a4 / 679784	RGDID:	1584758	Length:	495	Species:	Rattus norvegicus

Alignment Length:	468	Identity:	144/468 - (30%)
Similarity:	243/468 - (51%)	Gaps:	31/468 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 VRHVQCILCFFCLAMSYAWRVNLSVALVAMTDNSTSLAQNNTNTGV-APSEPGFDFFN------S 79
            :||....:...|....|..::|||:|:.||.  :|:.|.::.|..: .|:....||:|      .
  Rat    35 LRHGLAFILHLCNFSVYTQQMNLSIAITAMV--NTTAASSHANASIERPTTDSQDFWNETLQESK 97

  Fly    80 ERYYNFTQKEKGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITMLSPMSLQFGWV 144
            ...|::|.:.:|.|.:|..:|..:..:|.||:|..:|||.::..||.:::::|:..|::.:.|..
  Rat    98 APVYDWTPEIQGILLSSLNYGSFLAPIPTGYVAGVFGAKYVVGLGLLVSSVLTLFIPLAAEAGVA 162

  Fly   145 ALAVMRFVMGLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFGTVVMLATSGFIADSVLGW 209
            .|.|:|.:.|::|..|....:::.|||:|..||..|.|:..||:..||.::|...|.:..: |||
  Rat   163 LLIVLRVIQGMSQVMVLTGQYSMWAKWAPPLERSQLITIAASGSMLGTFLVLIAGGLLCQA-LGW 226

  Fly   210 PSIFYLGGACGFIWMVFWYLFSASTPEEHRLISPGELKYITDSRSDGKMQSAEKLAPTPWKAIFS 274
            |.|||:.|..|....:.|:......|:.|..||.||.:||..|.:.........|   |.||:..
  Rat   227 PYIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGEKRYIMCSLAQEDCSLGWSL---PIKAMVK 288

  Fly   275 SLPFLSLLVVHCTHIFGYWLL---LMQIPTYMKKIYHVDIKKGALLSSLPYM---VMLLLSFFFV 333
            |||..:::|   ::...||||   :...|||:..:...:::...:||:||:|   |.::|...
  Rat   289 SLPLWAIVV---SYFCEYWLLFTIMAYTPTYISSVLQANLRDSGILSALPFMFGCVCIILGGL-- 348

  Fly   334 WLSKVLQKKEGMSLSFNRKIFNSIGHWIPMLSLIALGYVPADNAPLAVTL--LTLTVGISGATYL 396
             |:..|..:..:.|...||:|.::|..:....|:.|.:|   ::.|:.|:  |.|:...:.....
  Rat   349 -LADFLLSRNILRLVTIRKLFTALGVLVSSGILVPLPWV---SSSLSTTMAFLVLSSVFASLCDS 409

  Fly   397 GFQVNHIDLSPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAFYFLGNL 461
            |..:|.:|::|.|||.|.|:....:.:..||||.:.| ..:.:.|...||.|||||||...:|.|
  Rat   410 GALINFLDIAPRYAGFLKGLLQVFSYLAGGIAPTVAG-FFISQDSEFGWRNVFLLAAAIDVVGLL 473

  Fly   462 LFVIFGRTEVQWW 474
            .::||||.|||.|
  Rat   474 FYLIFGRAEVQDW 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	144/468 (31%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	119/392 (30%)
Slc17a4	NP_001258143.1	MFS_SLC17	40..479	CDD:340876	135/454 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342519
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840