DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS14 and slc37a1

DIOPT Version :9

Sequence 1:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001007440.1	Gene:	slc37a1 / 492798	ZFINID:	ZDB-GENE-041114-151	Length:	529	Species:	Danio rerio

Alignment Length:	507	Identity:	114/507 - (22%)
Similarity:	177/507 - (34%)	Gaps:	133/507 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 NLSVALVAMTDNSTSLAQNNTNTGVAPSEPGFDF----FNSERYYNFTQKEKGNLQASFFFGYIV 103
            |.|.|:.|.|:.|:|..|..       ..|.||.    |:...|    ::..|.:..||.|.|.:
Zfish    52 NCSHAVEAPTEISSSSQQPG-------HHPEFDCSWKPFDRNNY----KQLLGAMDYSFLFAYAI 105

  Fly   104 TQVPGGYIAQRYGAKTMLMYGLGIAALITMLSPMSLQFGWVALAVMRFVM---GLAQGAVHPATH 165
            .....|.|.:|...:..|..|:..:.|.|.|..:...:...:|....||.   ||.|....|:..
Zfish   106 GMFLSGIIGERLPIRLYLTVGMLTSGLFTCLFGLGYIYDIHSLGFYIFVQVANGLVQTTGWPSVV 170

  Fly   166 ALLAKWSPADERGMLGTLCYSGAQFGTVVMLATSGFIADSVLGWPSIFYLGG----ACGFIWMVF 226
            ..:..|.....||::..|..|....|.::....:|:...|  .|...|.:.|    |.|.|  .|
Zfish   171 TCIGNWFGKGRRGLIMGLWNSHTSVGNILGSLIAGYYVSS--NWGLSFIVPGVIIAAMGVI--CF 231

  Fly   227 WYLF-----------SASTPEEHRL----------------ISPG------ELKYITDSRSDGKM 258
            ::|.           .:|.|...:.                ..||      :.:.:....|.|..
Zfish   232 FFLIEHPNDLKTASTQSSAPSSQKFHKSCNGVNGHKDLYLQYKPGAKAQSWDTELLLGQESIGVC 296

  Fly   259 QSAEKLAPTPWKAIFSSLPFLSLL----VVH---C-------THIFGYWLLLMQIPTYMKKIYHV 309
            ...:::.....:|..|::.|:..|    ||.   |       ::.|.:||     |.|:.|..|:
Zfish   297 VPVQQVVVVKSEAEPSAISFMGALRIPGVVEFSLCLLFAKLVSYTFLFWL-----PLYITKAAHL 356

  Fly   310 DIKKGALLSSL------------------------PYMVMLLLSFFFVWLSKVLQKKEGMSLSFN 350
            |.||...||:|                        ...|||||:             ..|...|:
Zfish   357 DAKKAGDLSTLFDVGGIVGGILAGVISDKMHKRATTCAVMLLLA-------------APMLYGFS 408

  Fly   351 RKIFNSIGHWIPMLSLIALGYVPADNAPLAVTLLTLTVGISGATYLGFQVNHIDLSPNYAGTLMG 415
            ......:|..|.|| |:..|.|   |.|.|  |:|..|.....|:...:.|...||     |:..
Zfish   409 MMSQFGLGPTIGML-LVCGGLV---NGPYA--LITTAVSADLGTHKSLKGNARALS-----TVTA 462

  Fly   416 ITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVF--LLAAAFYFLGNLLFVI 465
            |.:...:|.:.:.|::.|.:     |...|..||  |:.|.|:.|..||.::
Zfish   463 IIDGTGSVGAAVGPLLAGLL-----SARGWDQVFYMLMTADFFALLLLLRLV 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	114/507 (22%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	102/465 (22%)
slc37a1	NP_001007440.1	UhpC	92..501	CDD:332119	98/446 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582589
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840