DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS14 and CG3036

DIOPT Version :9

Sequence 1:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	155/500 - (31%)
Similarity:	261/500 - (52%)	Gaps:	25/500 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LTMVKTGGKYANEKFFGVRHVQCILCFFCLAMSYAWRVNLSVALVAMT-DNSTS-----LAQNNT 63
            ::..:.||......|...|.|..:|......::||.||||::|:|.|. .|.||     |..|:|
  Fly     1 MSNTEKGGLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNST 65

  Fly    64 NTGVAPSEPGFDFFNSERYYNFTQKEKGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIA 128
            ......|..|.|.:  |..:.:...:...:...||:|||:|::|||.:|:..|.:.:..:.:..|
  Fly    66 AANSTASPDGVDVY--EERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWA 128

  Fly   129 ALITMLSPMSLQFGWVALAVMRFVMGLAQGAVHPATHALLAKWSPADERG-MLGTLCYSGAQFGT 192
            :|:|:::|::....:|.|.|:|.|:|...||..||.|.:.|.|.|..||. .:..:..|  ..|.
  Fly   129 SLLTLITPLAAHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMAS--SLGA 191

  Fly   193 VVMLATSGFIADSVLGWPSIFYLGGACGFIWMVFWYLFSASTPEEHRLISPGELKYITDSRSDGK 257
            .:.:...|::. ||.||.|:|||.||.|.:|.:.|:.|...||..|..||..|.:.|.:  :.|.
  Fly   192 AITMPICGYLI-SVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEE--AIGT 253

  Fly   258 MQSAEKLAPTPWKAIFSSLPFLSLLVVHCTHIFGYWLLLMQIPTYMKKIYHVDIKKGALLSSLPY 322
            ..|.::.:..||..:..|....::::.|...:||::.::.|:||:|.||.|.|||:..|.|||||
  Fly   254 TTSKKRPSHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPY 318

  Fly   323 MVMLLLSFFFVWLSKVLQKKEGMSLSFNRKIFNSIGHWIPMLSLIA---LGYVPADNAPLAVTLL 384
            :...:::....:|:..|:||..:|.:..||:|.:....||.|.:|.   |||    :|..:||:.
  Fly   319 LGKYVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGY----DATWSVTIF 379

  Fly   385 TLTVGISGATYLGFQVNHIDLSPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVF 449
            :|.:...||...|:..|.:|::||:.||:.|:.|..::....::..:||.:...:.|...|::||
  Fly   380 SLALFAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVF 444

  Fly   450 LLAAAFYFLGNLLFVIFGRTEVQWWDSP----RDNKEDAEQGTPL 490
            .:.||.|....::|.|.|..|:|.|::|    |.:....|:|.||
  Fly   445 WILAATYISAAVVFAILGSGELQPWNNPPERVRISDVTQEEGVPL 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	147/467 (31%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	119/388 (31%)
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	147/468 (31%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	119/386 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970