DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS14 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_038951630.1	Gene:	Slc17a2 / 306950	RGDID:	1308821	Length:	487	Species:	Rattus norvegicus

Alignment Length:	483	Identity:	151/483 - (31%)
Similarity:	249/483 - (51%)	Gaps:	44/483 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VQCILCFFC-------LAMSYA------WRVNLSVALVAMT------DNSTSLAQ-------NNT 63
            |.|:...||       |.|.::      .||:||:|::||.      |.:.:.|:       :|.
  Rat    15 VSCLGSGFCSLRYALALVMHFSNFTMITQRVSLSIAIIAMVNSTQHQDPANASAEGPVMNLLSNR 79

  Fly    64 NTGVAPSEPGFDFFNSERYYNFTQKEKGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIA 128
            :.|:.      ||......|.::.:.:|.:.:|..:|.|:|.:|.||:|..:|||.:|..||.|:
  Rat    80 SRGIK------DFSTRAAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLIS 138

  Fly   129 ALITMLSPMSLQFGWVALAVMRFVMGLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFGTV 193
            :|:|:.:|::..||.:.:.|:|.|.|:|||........:.|||:|..||..|.::..|||.||:.
  Rat   139 SLLTLFTPLAADFGVILVIVIRTVQGMAQGMSWTGQFTIWAKWAPPLERSKLTSIAGSGAAFGSF 203

  Fly   194 VMLATSGFIADSVLGWPSIFYLGGACGFIWMVFWYLFSASTPEEHRLISPGELKYITDSRSDGKM 258
            ::|...|.|:.: ||||.|||:.|:.|.:..|.|:......|..|..||..|.:|||.|.:   .
  Rat   204 IILCVGGLISQA-LGWPFIFYIFGSIGCVCCVLWFTMIYDDPMHHPCISVKEKEYITSSVA---Q 264

  Fly   259 QSAEKLAPTPWKAIFSSLPFLSLLVVHCTHIFGYWL---LLMQIPTYMKKIYHVDIKKGALLSSL 320
            ||:......|.||:...||..::.:...:|   :||   ::..:|||:..:.||:|:...:||||
  Rat   265 QSSSPRRSIPIKAMVRCLPLWAIFMGFFSH---FWLCTIIITYLPTYISTVLHVNIRDSGVLSSL 326

  Fly   321 PYMVMLLLSFFFVWLSKVLQKKEGMSLSFNRKIFNSIGHWIPMLSLIALGYVPADNAPLAVTLLT 385
            |::.....:.....::..|..:..:||...||:|:|:|..:|.|..:||.:|.:... ..:.||.
  Rat   327 PFIAASSCTILGGQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFVTSSYI-ATIVLLI 390

  Fly   386 LTVGISGATYLGFQVNHIDLSPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFL 450
            |..|.|.....||.:|.:|::|.||..||||:. ...:.:||........::.:.|.:.||.||.
  Rat   391 LIPGTSNLCDSGFIINTLDVAPRYASFLMGISR-GFGLTAGIISSTTTGFLISQDSESGWRNVFF 454

  Fly   451 LAAAFYFLGNLLFVIFGRTEVQWWDSPR 478
            |:||....|.:.::|||:.|:|.|...|
  Rat   455 LSAAVNMFGLIFYLIFGQAEIQNWAKER 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	150/480 (31%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	125/387 (32%)
Slc17a2	XP_038951630.1	MFS_SLC17	30..471	CDD:340876	141/455 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342549
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750