DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS14 and SPAC11D3.18c

DIOPT Version :9

Sequence 1:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001342807.1	Gene:	SPAC11D3.18c / 2543005	PomBaseID:	SPAC11D3.18c	Length:	498	Species:	Schizosaccharomyces pombe

Alignment Length:	465	Identity:	100/465 - (21%)
Similarity:	176/465 - (37%)	Gaps:	101/465 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 FCLAMSYAWRVNLSVALVAMTDNSTSLAQNNTNTGVAPSEPGFDFFNSERYYNFTQKEKGNLQAS 96
            |...|::..|.|:..|.||....:.||.....|..|                           :.
pombe    67 FLYLMAFLDRSNIGNAAVAGMTEALSLYGERLNVAV---------------------------SI 104

  Fly    97 FFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITML-SPMSLQFGWVALAVMRFVMGLAQGAV 160
            |:..||:.:.|...:.:|..|..||.: :..|..:|:| |.....:|  .|...|.::||.:|.:
pombe   105 FYVLYILVETPSVVLVKRIKASRMLAF-ISFAWSMTVLFSGFMSSYG--GLIATRLILGLLEGCL 166

  Fly   161 HPATHALLAKWSPADERGMLGTLCYSGA----QFGTVVMLATSGFIADSVLGWPSIFYLGGACGF 221
            .||.:..|.......|:....:..::.|    .||.:...|.....|.:..||..|:.:.|...|
pombe   167 FPALNLYLTTHYTRKEQCQRLSYLFASAGLAGAFGGLFAYALEQVHAGNKEGWQWIYIVEGLVSF 231

  Fly   222 IWMVF------------WYLFSASTPEEHRLISPGELKYITDSRSDGKM----QSAEKLAPTPWK 270
            |.:..            |:|    |.||..:   ..::...::|..|:.    ....|....|..
pombe   232 IGVPLCLFALPDKMENAWFL----TREEREV---AIIRRDINARYHGEQHFEWSEVRKAFKDPKV 289

  Fly   271 AIFSSLPFLSLLVVHCTHIFGYWLLLMQIPTYMKKIYHVDIKKGALLSSLPYMVMLLLSFFFV-W 334
            .:.::..|.:.:|     ::|:...|   |..:|.:..|.::...:  ::|..:..::||.|| |
pombe   290 YVSATSQFCADMV-----LYGFSSFL---PVIIKGLGFVGLQTNYM--TIPVYIAGVISFLFVAW 344

  Fly   335 LSKVLQKKEGMSLSFNRKIFNSIGHWIPMLSLIALGYVPADNAPLAVTLLTLTVGISGATYLGFQ 399
            ||...|.:....:|.:              :::|:||:....:.......|.|..|:...|:|..
pombe   345 LSDRTQLRAVYLISAS--------------TVVAVGYIIMLASDSNAAKYTATYIIAIGCYIGPG 395

  Fly   400 VNHIDLSPNYAG-----TLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAF---- 455
            :|...|:.|.||     |.:||....|| .|||   :.|||...:.:..     ::|..||
pombe   396 LNLGWLNNNVAGHYKRATAIGIQQTLAN-SSGI---VAGQIYRSKNAPK-----YILGNAFTLGC 451

  Fly   456 YFLGNLLFVI 465
            ..:|.|.:|:
pombe   452 VIVGGLAYVV 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	100/465 (22%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	89/416 (21%)
SPAC11D3.18c	NP_001342807.1	UhpC	68..461	CDD:332119	98/462 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050