DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS14 and vht1

DIOPT Version :9

Sequence 1:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_594801.1	Gene:	vht1 / 2542518	PomBaseID:	SPAC1B3.16c	Length:	568	Species:	Schizosaccharomyces pombe

Alignment Length:	477	Identity:	102/477 - (21%)
Similarity:	175/477 - (36%)	Gaps:	114/477 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 VRHVQCILCFFCLAMSYAWRVNLSVALVAMTDNSTSLAQNNTNTGVAPSEPGFDFFNSERYYNFT 86
            :|.:.|:...:.|:....:.|:||..:  .|....||.|  |.:|                |:..
pombe    83 LRIIPCLWILYFLSCCLRFTVSLSFTM--NTAQGHSLIQ--TLSG----------------YSAH 127

  Fly    87 QKEKGNLQASFFFGYIVTQVPG----GYIAQR-YGAKTMLMYGLGIAALITMLSPMSLQFGWVAL 146
            ....|  .|.|:.|||:.:||.    .:|..| :.::..|..|:..|....:.:.......:|||
pombe   128 YLALG--LALFYVGYIIFEVPSNLMMAFIEPRIWVSRIQLTIGVVGACHAVLGTKHGNAQSYVAL 190

  Fly   147 AVMRFVMGLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQF-GTVVMLATSGFI----ADSV 206
               ||.:|:|:..:.|.....:::|......|......|:.||. ...|.|.::||.    |..:
pombe   191 ---RFFLGVAESGLWPGLAYYMSRWYRGKHLGKRIGWYYTAAQIAAAAVSLVSAGFQKMDGARGL 252

  Fly   207 LGWPSIFYLGG--ACGFIWMVFWYLFSASTPEEHR--------------LISPGELKYIT----- 250
            .|:..:|.:.|  |......:.|:| .|...:|||              .:||..:.::|
pombe   253 YGYQWMFLIWGVVAIAQALSIPWWL-PAVASKEHRKSLSSFIPLPKWMKTLSPQRIGFLTPADKS 316

  Fly   251 -DSRSDGKMQSAEKLAPTPWKAIFSSL------PFLSL---LVVHCTHIFGYWLLLMQ--IPTYM 303
             .||...:|...::   ..|..:..|.      ||:.:   :|.....||.|..|:::  .|::.
pombe   317 LHSRYIAEMNVGKR---WQWSDLLKSCLDLRVWPFILMYFGIVGVGNGIFNYCTLIIEEINPSFS 378

  Fly   304 KKIYHVDIKKGALLSSLPYMVMLLLSFFFVWLSKVLQKKEGMSL--SFNRKIFNSIGHWIPMLSL 366
                .:||.    |.:.|           :||:..|.....|.|  .|::|.....|..:    :
pombe   379 ----GIDIS----LLNAP-----------IWLADALGIVTVMPLYDRFHKKFSFFTGSCL----I 420

  Fly   367 IALGYVPADNAPLAVT----LLTLTVGISGATYLGFQVNHIDLSPNYAGTLMGITNCAANVMSGI 427
            |..|...|:.||.|.:    ||.:..|: |.|        :.:...:....|..|.....|.|.:
pombe   421 IIAGLAVANYAPRAWSRYGGLLMIGFGL-GPT--------VPICMAWCSASMAKTYGDVGVASSL 476

  Fly   428 APVI----VGQIVVDETSVTEW 445
            |.|.    :|.:|......:.|
pombe   477 ALVTGLGNLGSVVTTYALYSGW 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	102/477 (21%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	90/418 (22%)
vht1	NP_594801.1	HpaX	80..503	CDD:131385	102/477 (21%)
vht1	NP_594801.1	MFS	94..493	CDD:119392	99/459 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000