Protein Alignment MFS14 and SLC37A4

DIOPT Version :10

• Sequence 1: NP_652038.2
• Gene: MFS14 / 46085
• FlyBaseID: FBgn0010651
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_001157750.1
• Gene: SLC37A4 / 2542
• HGNCID: 4061
• Length: 451
• Species: Homo sapiens
• Alignment Length: 469
• Identity: 104/469 - (22%)
• Similarity: 165/469 - (35%)
• Gaps: 131/469 - (27%)

  Fly    77 FNSERYYNFTQK------------------EKGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMY 123
            |.....|.|.:|                  :.|.:.:|....|.:::...|.::.:..|:.:...
Human    18 FGGYSLYYFNRKTFSFVMPSLVEEIPLDKDDLGFITSSQSAAYAISKFVSGVLSDQMSARWLFSS 82

  Fly   124 GLGIAALITMLSPMSLQFGWVA----LAVMRFVMGLAQGAVHPATHALLAKWSPADERGMLGTLC 184
            ||.:..|:.:.      |.|.:    .|.:.|:.|||||...|....:|.||
Human    83 GLLLVGLVNIF------FAWSSTVPVFAALWFLNGLAQGLGWPPCGKVLRKW------------- 128

  Fly   185 YSGAQFGT-VVMLATS-------GFIADSVL----GWPSIFYLGGACGFIWMVFWYLFSASTPEE 237
            :..:|||| ..:|:||       |.|..::|    .|.|...|.||...:......|...:.|.:
Human   129 FEPSQFGTWWAILSTSMNLAGGLGPILATILAQSYSWRSTLALSGALCVVVSFLCLLLIHNEPAD 193

  Fly   238 HRLISPGELKYITDSRSDGKMQSAEK--------LAPTPWKAIFSSLPFLSLLVVHCTHIFGYWL 294
                  ..|:.:....|:||..|.::        |:|..|  :.|:...:...|..|...:|.:.
Human   194 ------VGLRNLDPMPSEGKKGSLKEESTLQELLLSPYLW--VLSTGYLVVFGVKTCCTDWGQFF 250

  Fly   295 LLMQIPTYMKKIYHVDIKKG--ALLSSLPYMVMLLL-----SFFFVWLSKVLQKKEGMSLSFNRK 352
            |:.:              ||  ||:.| .||..|.:     |....:||.....|.|:|...|.:
Human   251 LIQE--------------KGQSALVGS-SYMSALEVGGLVGSIAAGYLSDRAMAKAGLSNYGNPR 300

  Fly   353 ----IFNSIGHWIPM--LSLIALGYVPADNA-------PLA-VTLLT---LTVGISGATYLGFQ- 399
                :|...|..:.|  ..:......|.|.|       ||| :|..|   |.:.:.||.: ||.
Human   301 HGLLLFMMAGMTVSMYLFRVTVTSDSPKDVAFWTLALHPLAELTGFTEHELWILVLGAVF-GFSS 364

  Fly   400 ---------VNHIDLSPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLA--- 452
                     :.:....||..||...|....|||...:|.:....|....:    |...|.:|
Human   365 YGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYS----WSTAFWVAEVI 425

  Fly   453 -----AAFYFLGNL 461
                 |||:.|.|:
Human   426 CAASTAAFFLLRNI 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_652038.2	MFS_SLC17	27..467	CDD:340876	104/469 (22%)
SLC37A4	NP_001157750.1	MFS_SLC37A4	10..439	CDD:340901	103/467 (22%)