Protein Alignment MFS14 and cima-1

DIOPT Version :10

• Sequence 1: NP_652038.2
• Gene: MFS14 / 46085
• FlyBaseID: FBgn0010651
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_001294208.1
• Gene: cima-1 / 24104589
• WormBaseID: WBGene00018473
• Length: 543
• Species: Caenorhabditis elegans
• Alignment Length: 493
• Identity: 129/493 - (26%)
• Similarity: 221/493 - (44%)
• Gaps: 61/493 - (12%)

  Fly    30 CFFCLAMSYAWRVNLSVALVAMTDNSTSLAQNNTNTGVAPSEPGFDFFNSERYYNFTQKEKGNLQ 94
            ||..|::|.:   ||:|||:.||                 |.|...:..:   ..:..:::|.:.
 Worm    77 CFITLSISSS---NLAVALICMT-----------------SCPVHGYGGT---LEWQSQQEGLVL 118

  Fly    95 ASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITMLSPM--SLQFGWVALAVMRFVMGLAQ 157
            |:...|.::..|.|.: |.|...|.|:..||.:..:..::.|:  |..|.:..||  |..:|.:.
 Worm   119 AAQNAGSLIMIVTGMW-ADRLNGKWMVFIGLLLCCIGNLMLPLLASKSFWFAVLA--RISIGASD 180

  Fly   158 GAVHPATHALLAKWSPADERGMLGTLCYSGAQFGTVVMLATSGFIA---DSVLGWPSIFYLGGAC 219
            ..:.||.::|:.:|.|..||.....|...|.|.||:.:|.|:|::.   |.:.|||:||||....
 Worm   181 ACLMPAVNSLITRWFPQAERPAAIGLISGGRQIGTLFILPTAGYLCTRKDILDGWPAIFYLSATI 245

  Fly   220 GFIWMVFWYLFSASTPEEHRLISPGELKYITDSR----SDGKMQSAEKLAPTPWKAIFSSLPFLS 280
            ..:..|||..|.|..|.:...||..|.::| ::|    |.||  ..::....|:.|:..|.|..:
 Worm   246 SVLVTVFWIPFGADKPAKQICISSREKEFI-ETRIACESIGK--RTDRTRRVPYGAMLHSKPLWA 307

  Fly   281 LLVVHCTHIFGYWLLLMQIPTYMKKIYHVDIKKGALLSSLPYMVMLLLSFFFVWLSKVLQKKEGM 345
            .:.....|.:...::|..:|.||:.:......|..::::||.:.:.|...|...||..|..|..:
 Worm   308 CIFALICHEYPLVIMLQFLPNYMRDVLEFAPTKNGIIAALPILCLFLSKTFSSSLSSYLTTKLRL 372

  Fly   346 SLSFNRKIFNSIGHWIPMLSL-IALGYVP---ADNAPLAVTLLTLTVGISGATYLGFQVNHIDLS 406
            ..:|..|.||::.    ...| |.:.:||   .::|.|||..|...:..:|....|.....:.::
 Worm   373 DKTFVCKGFNAVA----SAGLAICISFVPFFNKESAFLAVFCLCGAMIFAGLHTPGVITAMVQIA 433

  Fly   407 PNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAFYFLGNLLFVIFGRTEV 471
            |.::|.:.|.:..|....| |...|:.:.:|...|||||.:||.::|....|..::|.|:|..:.
 Worm   434 PAFSGIITGWSFFAVAWFS-IGNKILTKYIVQSGSVTEWGMVFRVSALVAALPVIVFTIWGSADR 497

  Fly   472 QWWDSP--------------RDNKEDAEQGTPLAPNGQ 495
            :||.:|              ||...:..:.|.....||
 Worm   498 EWWAAPSSKCSVASFHRPSIRDRSREMSRATSSTSLGQ 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_652038.2	MFS_SLC17	27..467	CDD:340876	120/449 (27%)
cima-1	NP_001294208.1	2A0114euk	63..506	CDD:129972	124/462 (27%)