Protein Alignment MFS14 and SLC37A2

DIOPT Version :10

• Sequence 1: NP_652038.2
• Gene: MFS14 / 46085
• FlyBaseID: FBgn0010651
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_938018.1
• Gene: SLC37A2 / 219855
• HGNCID: 20644
• Length: 505
• Species: Homo sapiens
• Alignment Length: 526
• Identity: 109/526 - (20%)
• Similarity: 188/526 - (35%)
• Gaps: 117/526 - (22%)

  Fly    14 YANEKFFGVRHVQCILCFFCLAMSYAWRVNLSVALVAMTDNSTSLAQ--NNTNT-------GVAP 69
            ::.:.:|  |.:..:|.|...|..:..|..:|:....:..|.:...:  |:|::       ..||
Human    15 FSRDSWF--RGLILLLTFLIYACYHMSRKPISIVKSRLHQNCSEQIKPINDTHSLNDTMWCSWAP 77

  Fly    70 SEPGFDFFNSERYYNFTQKE-KGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITM 133
                   |:.:.|     || .|.:..:|...|.:.....|...:|...:..|..|:.::.|.|.
Human    78 -------FDKDNY-----KELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTS 130

  Fly   134 LSPMSLQFGWVALAVMRFVM-----GLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFGTV 193
            |  ..|.:.|....:..||:     ||.|....|:....:..|....:||.:..:..|....|.:
Human   131 L--FGLGYFWNIHELWYFVVIQVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNI 193

  Fly   194 VMLATSGFIADSVLGWPSIFYLGGACGFIWMVFWYLFSASTPEEHRLISP---GELKYITDSRSD 255
            :....:|...:.  .|...|.:.|....:..|..:||....||:.....|   ||.....|:..|
Human   194 LGSLIAGIWVNG--QWGLSFIVPGIITAVMGVITFLFLIEHPEDVDCAPPQHHGEPAENQDNPED 256

  Fly   256 ----------GKMQSAEKLAPTPWK-----AIFSSLPF-------LSLLVVH-CTHIFGYWLLLM 297
                      ..:::..|.:..|.:     :.|.:|..       |.||... .::.|.|||
Human   257 PGNSPCSIRESGLETVAKCSKGPCEEPAAISFFGALRIPGVVEFSLCLLFAKLVSYTFLYWL--- 318

  Fly   298 QIPTYMKKIYHVDIKKGALLSSL------------------------PYMVMLLLSFFFVWLSKV 338
              |.|:..:.|...|:...||:|                        ...|||:|:...::|...
Human   319 --PLYIANVAHFSAKEAGDLSTLFDVGGIIGGIVAGLVSDYTNGRATTCCVMLILAAPMMFLYNY 381

  Fly   339 LQKKEGMSLSFNRKIFNSIGHWIPMLSLIALGYVPADNAPLAVTLLTLTVGISGATYLGFQVNHI 403
            : .::|::.|            |.|| :|..|.|   |.|.|  |:|..|.....|:...:.|..
Human   382 I-GQDGIASS------------IVML-IICGGLV---NGPYA--LITTAVSADLGTHKSLKGNAK 427

  Fly   404 DLSPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAFYFLGNLLFVIFGR 468
            .||     |:..|.:...::.:.:.|::.|.|     |.|.|..||.:..:...|..||......
Human   428 ALS-----TVTAIIDGTGSIGAALGPLLAGLI-----SPTGWNNVFYMLISADVLACLLLCRLVY 482

  Fly   469 TEVQWW 474
            .|:..|
Human   483 KEILAW 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_652038.2	MFS_SLC17	27..467	CDD:340876	105/504 (21%)
SLC37A2	NP_938018.1	MFS_SLC37A1_2	22..484	CDD:340902	106/511 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..262		5/21 (24%)