DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS14 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_006516709.1	Gene:	Slc17a2 / 218103	MGIID:	2443098	Length:	480	Species:	Mus musculus

Alignment Length:	480	Identity:	144/480 - (30%)
Similarity:	238/480 - (49%)	Gaps:	37/480 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 FFGVRHVQCILCFFCLAMSYAWRVNLSVALVAMTDNSTSLAQ--------------NNTNTGVAP 69
            |..:|:...::..|........||:||:|::||. |||....              :|.:.|:.
Mouse    13 FCSLRYALALIMHFSNFTMITQRVSLSIAIIAMV-NSTQHQDPANASTEGPVMDLLSNQSRGIK- 75

  Fly    70 SEPGFDFFNSERYYNFTQKEKGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITML 134
                 ||......|.::.:.:|.:.:|..:|.|:|.:|.||:|..:|||.:|..||.|::|:|:.
Mouse    76 -----DFSTRAAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLF 135

  Fly   135 SPMSLQFGWVALAVMRFVMGLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFGTVVML--A 197
            :|::..||.:.:.|:|.|.|:|||........:.|||:|..||..|.::..||...|:|.:|  .
Mouse   136 TPLAADFGVILVIVIRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTSIAGSGEDVGSVWVLHHP 200

  Fly   198 TSGFIADSVLGWPSIFYLGGAC-GFIWMVFWYLFSASTPEEHRLISPGELKYITDSRSDGKMQSA 261
            ..|.|  ::.|....|||...| |.:..|.|:......|..|..||..|.::||.|.:   .||:
Mouse   201 LCGRI--NLTGTGLAFYLLHLCIGCVCCVLWFTVIYDDPMHHPCISVREKEHITSSVA---QQSS 260

  Fly   262 EKLAPTPWKAIFSSLPFLSLLVVHCTHIFGYWL---LLMQIPTYMKKIYHVDIKKGALLSSLPYM 323
            ......|.||:...||..::.:...:|   :||   ::..:|||:..:.||:|:...:|||||::
Mouse   261 SPRRSVPIKAMVRCLPLWAIFMGFFSH---FWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFI 322

  Fly   324 VMLLLSFFFVWLSKVLQKKEGMSLSFNRKIFNSIGHWIPMLSLIALGYVPADNAPLAVTLLTLTV 388
            .....:.....::..|..:..:||...||:|:|:|..:|.|..:||.:|.:... ..:.||.|..
Mouse   323 AASSCTILGGQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFVTSSYI-ATIVLLILIP 386

  Fly   389 GISGATYLGFQVNHIDLSPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAA 453
            |.|.....||.:|.:|::|.||..||||:. ...:.:||........::.:.|.:.||.||.|:|
Mouse   387 GTSNLCDSGFIINTLDVAPRYASFLMGISR-GFGLTAGIISSTTTGFLISQDSESGWRNVFFLSA 450

  Fly   454 AFYFLGNLLFVIFGRTEVQWWDSPR 478
            |....|.:.::|||:.|:|.|...|
Mouse   451 AVNMFGLIFYLIFGQAEIQSWAKER 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	143/477 (30%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	120/390 (31%)
Slc17a2	XP_006516709.1	MFS_SLC17	21..464	CDD:340876	136/459 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838742
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750