DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS14 and Slc17a7

DIOPT Version :9

Sequence 1:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_038966881.1	Gene:	Slc17a7 / 116638	RGDID:	620101	Length:	585	Species:	Rattus norvegicus

Alignment Length:	483	Identity:	151/483 - (31%)
Similarity:	261/483 - (54%)	Gaps:	27/483 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 FGV--RHVQCILCFFCLAMSYAWRVNLSVALVAMTDNSTS------LAQN-----NTNTGVAPSE 71
            ||:  |::..|:......:|:..|.||.||:|:|.:|||:      :.|.     :....|.|:.
  Rat    57 FGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQTPYRSVHKQEAVTPTV 121

  Fly    72 PGFDFFNSER-YYNFTQKEKGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITMLS 135
            ......::|: .:|:..:..|.:..|||:||||||:|||:|.|::.|..:..:.:...:.:.||.
  Rat   122 GDIQGGDTEKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLI 186

  Fly   136 PMSLQFGWVALAVMRFVMGLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFGTVVMLATSG 200
            |.:.:..:..:..:|.:.||.:|..:||.|.:.:||:|..||..|.|..:.|:..|.||.:..:|
  Rat   187 PSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAG 251

  Fly   201 FIADSVLGWPSIFYLGGACGFIWMVFWYLFSASTPEEHRLISPGELKYITDSRSDGKMQSAEKLA 265
            .:. ...||.|:||:.|:.|..|.:||.|.|..:|..|..||..|.|||.|:..    :||:.:.
  Rat   252 VLV-QYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIG----ESAKLMN 311

  Fly   266 P-----TPWKAIFSSLPFLSLLVVHCTHIFGYWLLLMQIPTYMKKIYHVDIKKGALLSSLPYMVM 325
            |     |||:..|:|:|..:::|.:....:.::|||:..|.|.::::..:|.|..|:|:||::||
  Rat   312 PVTKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVM 376

  Fly   326 LLLSFFFVWLSKVLQKKEGMSLSFNRKIFNSIGHWIPMLSLIALGYVPADNAPLAVTLLTLTVGI 390
            .::......::..|:.:..||.:..||:.|..|..:....|:.:||  :.:..:|::.|.|.||.
  Rat   377 TIIVPIGGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLVVGY--SHSKGVAISFLVLAVGF 439

  Fly   391 SGATYLGFQVNHIDLSPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAF 455
            ||....||.|||:|::|.||..||||:|....:...:.|:|||.:...:|. .||:.|||:|:..
  Rat   440 SGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHKTR-EEWQYVFLIASLV 503

  Fly   456 YFLGNLLFVIFGRTEVQWWDSPRDNKED 483
            ::.|.:.:.:|...|.|.|..|.:..|:
  Rat   504 HYGGVIFYGVFASGEKQPWAEPEEMSEE 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	149/475 (31%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	126/390 (32%)
Slc17a7	XP_038966881.1	MFS_SLC17A6_7_8_VGluT	66..515	CDD:340940	142/456 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342465
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850