Protein Alignment MFS14 and Slc17a3

DIOPT Version :10

• Sequence 1: NP_652038.2
• Gene: MFS14 / 46085
• FlyBaseID: FBgn0010651
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_598830.2
• Gene: Slc17a3 / 105355
• MGIID: 2389216
• Length: 498
• Species: Mus musculus
• Alignment Length: 503
• Identity: 144/503 - (28%)
• Similarity: 239/503 - (47%)
• Gaps: 35/503 - (6%)

  Fly     1 MTTALTMVKTG-------GKYANEK--------FFGVRHVQCILCFFCLAMSYAWRVNLSVALVA 50
            |.|.:.|..|.       |...|:|        ...:|:....:..||.....|....:|:.:||
Mouse     1 MATVVEMSPTSEQSEFVLGTPVNKKTPALKVPSLCSMRYGIAFVTHFCNFTLMAQNSIISITMVA 65

  Fly    51 MTDNSTSLAQNNTNTGVAPSEPGFDFFNSERY-------YNFTQKEKGNLQASFFFGYIVTQVPG 108
            |.:|:......|::|...|:....|...:.::       ||::.:.:|.:.:|..:|.|:.|.||
Mouse    66 MVNNTDHPPHLNSSTEQLPAGLSGDQHEASKHLPIKAPVYNWSPQTQGIIFSSVQYGMILMQGPG 130

  Fly   109 GYIAQRYGAKTMLMYGLGIAALITMLSPMSLQFGWVALAVMRFVMGLAQGAVHPATHALLAKWSP 173
            ||:|.:.|.|.::...|..::|:|:..|::...|.|.....|.|.||.||..:....||..||:|
Mouse   131 GYLAGKIGTKKVVGIALLGSSLLTLCIPLAANLGLVFFLATRAVQGLMQGTGYGGQFALWQKWAP 195

  Fly   174 ADERGMLGTLCYSGAQFGTVVMLATSGFIADSVLGWPSIFYLGGACGFIWMVFWYLFSASTPEEH 238
            .:||..|.|:..||...|...:|...|.|::: ||||.:||..|..|.:..:.|::.....|..|
Mouse   196 PNERSRLCTIALSGMTLGIFTVLLVGGIISEA-LGWPFVFYSFGGGGVLCSLLWFILIYDDPVSH 259

  Fly   239 RLISPGELKYITDSRSDGKMQSAEKLAPTPWKAIFSSLPFLSLLVVHCTHIFGYWLL---LMQIP 300
            ..||..|.:||..|.:   .|.:.:..|.|.||:..|||..|:.:...||   .||:   :|..|
Mouse   260 PWISGPEREYILSSLN---QQFSSEEQPLPIKAMLKSLPLWSMCLCTMTH---QWLVNTFIMYTP 318

  Fly   301 TYMKKIYHVDIKKGALLSSLPYMVMLLLSFFFVWLSKVLQKKEGMSLSFNRKIFNSIGHWIPMLS 365
            ||:..::.|:|:....|||||::|..:|.....||:..|..| ...|...||....:|:..|...
Mouse   319 TYISSVFKVNIRDNGFLSSLPFIVAWVLGILGGWLADFLLSK-NFRLITVRKFITLLGNAPPAAL 382

  Fly   366 LIALGYVPADNAPLAVTLLTLTVGISGATYLGFQVNHIDLSPNYAGTLMGITNCAANVMSGIAPV 430
            :.||.|:.:... ..:..||::.|:...:..|..:|.:|::|.||..|||.:...|:..:.:.|:
Mouse   383 VAALPYIQSSYI-TTIIFLTISCGLCPLSQAGIYINALDIAPRYASFLMGTSRGLAHSSAVLVPI 446

  Fly   431 IVGQIVVDETSVTEWRLVFLLAAAFYFLGNLLFVIFGRTEVQWWDSPR 478
            :.| ..:.:.|...||..|.:..|...||.:::::||:.:||.|...|
Mouse   447 VAG-FFLSQDSEFGWRNFFFVVFAVNLLGLIIYLVFGKADVQEWARER 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_652038.2	MFS_SLC17	27..467	CDD:340876	130/449 (29%)
Slc17a3	NP_598830.2	MFS_SLC17	42..482	CDD:340876	130/449 (29%)