Protein Alignment MFS14 and SLC17A2

DIOPT Version :10

• Sequence 1: NP_652038.2
• Gene: MFS14 / 46085
• FlyBaseID: FBgn0010651
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: XP_054209984.1
• Gene: SLC17A2 / 10246
• HGNCID: 10930
• Length: 487
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 142/507 - (28%)
• Similarity: 249/507 - (49%)
• Gaps: 46/507 - (9%)

  Fly    12 GKYANEK---FFGVRHVQCILCFFCLAMSYAWRVNLSVALVAMTDNSTSLAQNNTNTGVAPSEPG 73
            ||.|..|   |..:|:...::..|........||:||:|::||.:.:.....:|.:|    ..|.
Human     3 GKPATRKGPDFCSLRYGLALIMHFSNFTMITQRVSLSIAIIAMVNTTQQQGLSNAST----EGPV 63

  Fly    74 FDFFNSE-----------RYYNFTQKEKGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGI 127
            .|.||:.           ..|.::.:.:|.:.:|..:|.|:|.:|.||:|..:|||.||..||.|
Human    64 ADAFNNSSISIKEFDTKASVYQWSPETQGIIFSSINYGIILTLIPSGYLAGIFGAKKMLGAGLLI 128

  Fly   128 AALITMLSPMSLQFGWVALAVMRFVMGLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFGT 192
            ::|:|:.:|::..||.:.:.::|.|.|:|||........:.|||:|..||..|.|:..||:.||:
Human   129 SSLLTLFTPLAADFGVILVIMVRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTTIAGSGSAFGS 193

  Fly   193 VVMLATSGFIADSVLGWPSIFYLGGACGFIWMVFWYLFSASTPEEHRLISPGELKYITDSRSDGK 257
            .::|...|.|:.: |.||.|||:.|:.|.:..:.|:......|..|..||..|.::|..|.:
Human   194 FIILCVGGLISQA-LSWPFIFYIFGSTGCVCCLLWFTVIYDDPMHHPCISVREKEHILSSLA--- 254

  Fly   258 MQSAEKLAPTPWKAIFSSLPFLSLLVVHCTHIFGYWL---LLMQIPTYMKKIYHVDIKKGALLSS 319
            .|.:......|.||:.:.||..::.:...:|   :||   :|..:|||:..:.||:|:...:|||
Human   255 QQPSSPGRAVPIKAMVTCLPLWAIFLGFFSH---FWLCTIILTYLPTYISTLLHVNIRDSGVLSS 316

  Fly   320 LPYMVMLLLSFFFVWLSKVLQKKEGMSLSFNRKIFNSIGHWIPMLSLIALGYVPADNAPLAVTLL 384
            ||::.....:.....|:..|..:..:.|...||:|:|:|..:|.:..:||.:| |.:..:.:.||
Human   317 LPFIAAASCTILGGQLADFLLSRNLLRLITVRKLFSSLGLLLPSICAVALPFV-ASSYVITIILL 380

  Fly   385 TLTVGISGATYLGFQVNHIDLSPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVF 449
            .|..|.|.....||.:|.:|::|.||..||||:. ...:::||........::.:..:..
Human   381 ILIPGTSNLCDSGFIINTLDIAPRYASFLMGISR-GFGLIAGIISSTATGFLISQVGILS----- 439

  Fly   450 LLAAAFYFLGNLLF-VIFGRTEVQWWDSPRDNKEDAEQGT---PLAPNGQVK 497
                   .:|.:.| .:...|.:.|..:.|.:|::.:.|.   ||..:..:|
Human   440 -------LVGGMSFSCLLQSTCLAWSFTSRLDKQNFKTGPKRGPLPASEDIK 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_652038.2	MFS_SLC17	27..467	CDD:340876	128/454 (28%)
SLC17A2	XP_054209984.1	MFS_SLC17	21..434	CDD:340876	126/425 (30%)