Protein Alignment MFS14 and SLC17A4

DIOPT Version :9

• Sequence 1: NP_001286591.1
• Gene: MFS14 / 46085
• FlyBaseID: FBgn0010651
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_005486.1
• Gene: SLC17A4 / 10050
• HGNCID: 10932
• Length: 497
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 143/473 - (30%)
• Similarity: 238/473 - (50%)
• Gaps: 33/473 - (6%)

  Fly    19 FFGVRHVQCILCFFCLAMSYAWRVNLSVALVAMTDNSTSLAQNNTNTGVAPSEPGFDFFNSERYY 83
            |..|||...::...|....|..::|||:|:.||.:|:...:|.|.:|    ..|..|   |:.|:
Human    32 FCSVRHGLALILQLCNFSIYTQQMNLSIAIPAMVNNTAPPSQPNAST----ERPSTD---SQGYW 89

  Fly    84 NFTQKE--------------KGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITML 134
            |.|.||              :|.:.:|..:|..:..:|.||:|..:|||.::..||.|::.:|:.
Human    90 NETLKEFKAMAPAYDWSPEIQGIILSSLNYGSFLAPIPSGYVAGIFGAKYVVGAGLFISSFLTLF 154

  Fly   135 SPMSLQFGWVALAVMRFVMGLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFGTVVMLATS 199
            .|::...|...|.|:|.|.|:||..|....:::..||:|..||..|.|:..||:..|:.::|...
Human   155 IPLAANAGVALLIVLRIVQGIAQVMVLTGQYSIWVKWAPPLERSQLTTIAGSGSMLGSFIVLLAG 219

  Fly   200 GFIADSVLGWPSIFYLGGACGFIWMVFWYLFSASTPEEHRLISPGELKYITDSRSDGKMQSAEKL 264
            |.:..:: |||.:||:.|..|......|:......|..|..||.||.:||..|.:.........|
Human   220 GLLCQTI-GWPYVFYIFGGIGCACCPLWFPLIYDDPVNHPFISAGEKRYIVCSLAQQDCSPGWSL 283

  Fly   265 APTPWKAIFSSLPFLSLLVVHCTHIFGYWL---LLMQIPTYMKKIYHVDIKKGALLSSLPYMVML 326
               |.:|:..|||..::||   ::...|||   ::...|||:..:...:::...:||:||::|..
Human   284 ---PIRAMIKSLPLWAILV---SYFCEYWLFYTIMAYTPTYISSVLQANLRDSGILSALPFVVGC 342

  Fly   327 LLSFFFVWLSKVLQKKEGMSLSFNRKIFNSIGHWIPMLSLIALGYVPADNAPLAVTLLTLTVGIS 391
            :.......|:..|..::.:.|...||:|.:||...|.:.|::|.:|.:.:: :.:|.|.|:..||
Human   343 ICIILGGLLADFLLSRKILRLITIRKLFTAIGVLFPSVILVSLPWVRSSHS-MTMTFLVLSSAIS 406

  Fly   392 GATYLGFQVNHIDLSPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAFY 456
            .....|..||.:|::|.|.|.|.|:....|::...|:|...| ..:.:.|...||.||||:||..
Human   407 SFCESGALVNFLDIAPRYTGFLKGLLQVFAHIAGAISPTAAG-FFISQDSEFGWRNVFLLSAAVN 470

  Fly   457 FLGNLLFVIFGRTEVQWW 474
            ..|.:.::||||.:||.|
Human   471 ISGLVFYLIFGRADVQDW 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	143/473 (30%)
		MFS	81..466	CDD:119392	117/401 (29%)
SLC17A4	NP_005486.1	UhpC	30..491	CDD:332119	143/473 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148624
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5542
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.690