DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS14 and slc17a8

DIOPT Version :9

Sequence 1:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_002936892.1	Gene:	slc17a8 / 100489470	XenbaseID:	XB-GENE-988965	Length:	588	Species:	Xenopus tropicalis

Alignment Length:	465	Identity:	149/465 - (32%)
Similarity:	244/465 - (52%)	Gaps:	29/465 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 FCLAMSYAWRVNLSVALVAMTDNSTSLAQNNTNTGVAPSEPGFDFFNSERYYNFTQKEKGNLQAS 96
            ||:  |:..|.||.||:|.|.:|         ||.....:|..    .:..:|:..:..|.:..|
Frog    86 FCI--SFGIRCNLGVAIVEMVNN---------NTVYVDGKPEM----QKAQFNWDPETVGLIHGS 135

  Fly    97 FFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITMLSPMSLQFGWVALAVMRFVMGLAQGAVH 161
            ||:|||:||:|||:||.:..|..:....:.:.:::.||.|.:.:..:..:..:|.:.||.:|..:
Frog   136 FFWGYIITQIPGGFIANKLAANRVFGAAIFLTSILNMLIPSAARVHFGCVISVRVLQGLVEGVTY 200

  Fly   162 PATHALLAKWSPADERGMLGTLCYSGAQFGTVVMLATSGFIADSVLGWPSIFYLGGACGFIWMVF 226
            ||.|.:.:||:|..||..|.|..:.|:..|.|:.:..:|.:. ..:||||:||:.|..|..|.||
Frog   201 PACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGVLV-QYIGWPSVFYIYGVFGMCWYVF 264

  Fly   227 WYLFSASTPEEHRLISPGELKYITDSRSDGKMQSAEKLAPTPWKAIFSSLPFLSLLVVHCTHIFG 291
            |.|.:..:|..|..|:..|..||..|..:|..........||||..|:|:|..:::|.:....:.
Frog   265 WLLHATESPAAHPSITFEERTYIETSIGEGSNLVTTGKFKTPWKKFFTSMPVYAIIVANFCRSWT 329

  Fly   292 YWLLLMQIPTYMKKIYHVDIKKGALLSSLPYMVMLLLSFFFVWLSKVLQKKEGMSLSFNRKIFNS 356
            ::|||:..|.|.::::...|.|..|||::|:|||.::......|:..|:.::.:|.:..|||.|.
Frog   330 FYLLLISQPAYFEEVFGFPISKVGLLSAVPHMVMTIIVPVGGQLADFLRSRKILSTTTVRKIMNC 394

  Fly   357 IGHWIPMLSLIALGYVPADNAPLAVTLLTLTVGISGATYLGFQVNHIDLSPNYAGTLMGITNCAA 421
            .|..:....|:.:||  :....::::.|.|.||.||....||.|||:|::|.||..||||:|...
Frog   395 GGFGMEATLLLVVGY--SHTKAISISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVG 457

  Fly   422 NVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAFYFLGNLLFVIFGRTEVQWWDSPR-------- 478
            .:...:.|:|||.:..::|. .||:.|||:||..::.|.:.:.||...|.|.|..|.
Frog   458 TLSGMVCPLIVGAMTKNKTR-EEWQNVFLIAAIVHYSGVIFYGIFASGEKQEWADPESLSEDKCG 521

  Fly   479 --DNKEDAEQ 486
              ||.|.||:
Frog   522 IIDNDELAEE 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	143/444 (32%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	124/384 (32%)
slc17a8	XP_002936892.1	2A0114euk	75..513	CDD:129972	143/445 (32%)
slc17a8	XP_002936892.1	MFS	81..502	CDD:119392	139/434 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010