DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS14 and slc17a7b

DIOPT Version :9

Sequence 1:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_009295917.2	Gene:	slc17a7b / 100331980	ZFINID:	ZDB-GENE-131125-32	Length:	585	Species:	Danio rerio

Alignment Length:	470	Identity:	148/470 - (31%)
Similarity:	252/470 - (53%)	Gaps:	26/470 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 FGV--RHVQCILCFFCLAMSYAWRVNLSVALVAMTDNSTSLAQNNTNTGVAPSEPGFDFFNSERY 82
            ||:  |::..||......:|:..|.||.||:|:|.:|.|.......             :..:..
Zfish    57 FGLPRRYIIAILSGLGFCISFGIRCNLGVAVVSMVNNHTVYRDGKP-------------YIVKAQ 108

  Fly    83 YNFTQKEKGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITMLSPMS--LQFGWVA 145
            :::..:..|.:..|||:||||||:|||:|.|::.|..:..:.:...:::.|:.|.:  :.||.|.
Zfish   109 FSWDPETVGMIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAVVSTSILNMMIPTAARMHFGCVI 173

  Fly   146 LAVMRFVMGLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFGTVVMLATSGFIADSVLGWP 210
            |  :|.:.||.:|..:||.|.:.|||:|..||..|.|..:.|:..|.|:.:..:|.:. ...||.
Zfish   174 L--VRILQGLVEGVSYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVIAMPLAGVLV-QYSGWS 235

  Fly   211 SIFYLGGACGFIWMVFWYLFSASTPEEHRLISPGELKYITDS--RSDGKMQSAEKLAPTPWKAIF 273
            |:||:.|:.|..|.:||.|.|..:|..|..|:|.|.|||.|:  .|.|.:....|. .|||:..|
Zfish   236 SVFYVYGSFGVCWYLFWILVSYESPAAHPTITPEERKYIEDAIGESAGLVNPLTKF-NTPWRQFF 299

  Fly   274 SSLPFLSLLVVHCTHIFGYWLLLMQIPTYMKKIYHVDIKKGALLSSLPYMVMLLLSFFFVWLSKV 338
            :|:|..:::|.:....:.::|||:..|.|.::::..:|.|..:||:||::||.::......|:..
Zfish   300 TSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFKFEISKVGILSALPHLVMTIVVPIGGQLADY 364

  Fly   339 LQKKEGMSLSFNRKIFNSIGHWIPMLSLIALGYVPADNAPLAVTLLTLTVGISGATYLGFQVNHI 403
            |:....|:.:..||:.|..|..:....|:.:|:  :....:|::.|.|.||.||....||.|||:
Zfish   365 LRTHNLMTTTNVRKLMNCGGFGLEATFLLVVGF--SHTKGVAISFLVLAVGFSGFAISGFNVNHL 427

  Fly   404 DLSPNYAGTLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAFYFLGNLLFVIFGR 468
            |::|.||..||||:|....:...:.|:|||.:..::|. .||:.|||:|:..::.|.:.:.:|..
Zfish   428 DIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKNKTR-EEWQYVFLIASLVHYGGVIFYGLFAS 491

  Fly   469 TEVQWWDSPRDNKED 483
            .|.|.|..|.:..|:
Zfish   492 GEKQPWAEPENTSEE 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	146/462 (32%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	127/388 (33%)
slc17a7b	XP_009295917.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582487
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750