Protein Alignment vlc and DLGAP2

DIOPT Version :9

• Sequence 1: NP_001163056.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001333739.1
• Gene: DLGAP2 / 9228
• HGNCID: 2906
• Length: 1055
• Species: Homo sapiens
• Alignment Length: 609
• Identity: 126/609 - (20%)
• Similarity: 231/609 - (37%)
• Gaps: 152/609 - (24%)

  Fly    14 DVDADSSDISDTSGSLNFPTPVSVRDITREFTANLRERCVPNLPPQP---------------QHK 63
            :|::.:.|..|..|.....:...:|.|...::.:  :.|:|.:.|..               ..|
Human   550 EVESQAMDALDLPGCFRTRSHSYLRAIQAGYSQD--DECIPMMTPSDITSTIRSTAAVSYTNYKK 612

  Fly    64 TPAYVESRSSELEHMVLSPAI---VECDQEPSSNDFDETSAENSQEAPEKKPSYLNLACCV--NG 123
            ||..|..|::.      .|.|   .:...|.:.:.:.::.|:.....|:......|....:  |.
Human   613 TPPPVPPRTTS------KPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGLYNSTDSLDSNK 671

  Fly   124 YSNLTTYDSKIRQDINKSREVSPIRPSTSSLQYCKRNHFLATPTLHSMPSPATKCKPI------- 181
            ..||....:..::.:.:|:. |.:|.|..::...|....|           .::|..|
Human   672 AMNLALETAAAQRHLPESQS-SSVRTSDKAILVSKAEELL-----------KSRCSSIGIQDSEF 724

  Fly   182 -----EPNNNSNDSSGNFSSGSG----HSNGNGSFIKQRVERLYGPGALAQGFYSPKKHGQ-SPS 236
                 .|.::...::.:.:...|    ||.|      .:||             ..|:||: ..|
Human   725 PEHQPYPRSDVETATDSDTESRGLREYHSVG------VQVE-------------DEKRHGRFKRS 770

  Fly   237 NAAGRSERGQVEIDSLQGSELARKFKQLSPSKDYG-EFRKKMQKKCSQSTTARID--EPLHSPGL 298
            |:...:.:..:|::...|.         ..::|.| :|....|:....||..:..  ..:.:.||
Human   771 NSVTAAVQADLELEGFPGH---------ITTEDKGLQFGSSFQRHSEPSTPTQYSAVRTVRTQGL 826

  Fly   299 NGDLDLPVFRHLSQEFRAQLPTVSPKRGAPRSCMAPDVLLVDNESSPDHGPTDEVDHESTKMDKL 363
                    |.: .:::|.|:.|         |.:.|          ||......:|
Human   827 --------FSY-REDYRTQVDT---------STLPP----------PDPWLEPAID--------- 854

  Fly   364 ASEEYISTSNISVEAVVKDGNFFLKILKEEQSRLLVLAALAEKYADALSTNPDISEDTFGLLRSA 428
                .:.|..:|  ...:||::|||:|..|..|:.......|:.|:    ..|:||:..|.:|||
Human   855 ----TVETGRMS--PCRRDGSWFLKLLHAETKRMEGWCKEMEREAE----ENDLSEEILGKIRSA 909

  Fly   429 SGKARLLVSQKMKQFEGLCHNNLNRSPEDKFPTTLDDLQGFWDMVYLQVEHVDSIFADIEKLKSN 493
            .|.|:||:|||.:||..||..|::.|...: ||: .||.|:|||:.|.:|.|...|.::::|:.|
Human   910 VGSAQLLMSQKFQQFYWLCQQNMDPSAMPR-PTS-QDLAGYWDMLQLSIEDVSMKFDELQRLRLN 972

  Fly   494 DWKVKAQSVADQPDLHTIPTKTIKPSKVGVSQVKTVGKASSVRVNGSAPPPPNSAAALKREAQRK 558
            |||: .:|...:.:....|....||.|         ||....|......|...     ::||:|:
Human   973 DWKM-MESPERKEERKVPPPIPKKPPK---------GKFPITREKSLDLPDRQ-----RQEARRR 1022

  Fly   559 LLLEMKRQRREAMTAAAKLNPINV 582
            |:...:.......:|:.:.:.|.:
Human  1023 LMAAKRAASFRQNSASERADSIEI 1046

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_001163056.1	GKAP	246..575	CDD:281368	82/331 (25%)
DLGAP2	NP_001333739.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000823
OrthoInspector	1	1.000	-	-		otm41036
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12353
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3941
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.130