Protein Alignment vlc and dlgap4b

DIOPT Version :9

• Sequence 1: NP_001163056.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_697562.6
• Gene: dlgap4b / 569107
• ZFINID: ZDB-GENE-101215-2
• Length: 1081
• Species: Danio rerio
• Alignment Length: 660
• Identity: 158/660 - (23%)
• Similarity: 252/660 - (38%)
• Gaps: 154/660 - (23%)

  Fly     4 SLDSIGSCSLDVDADSSDISDTSGSLNFPTPVS-VRD--ITREFTANLRE-----RC--VPNLPP 58
            :||.||..|...:.|..|.|....:|...:.:| :||  :::.:...|.:     ||  .|::|
Zfish   486 NLDCIGGGSPFPNWDDDDFSQGCSTLGRGSCISQMRDMEMSQHYADELEDIHPHPRCSDPPDVP- 549

  Fly    59 QPQHKTPAYVESRSSELEHMVLSPAIVECDQEPSSNDFDETSAENSQEAPEKKPSYLNLACCVNG 123
                 .|....|||    |..|......|.|:      |:|::.:|...|.      .....|..
Zfish   550 -----MPTCFRSRS----HSYLRAIQAGCSQD------DDTASMDSDSPPP------TTTTTVRT 593

  Fly   124 YSNLTTYDSKIRQDINKSREVS--PIRPSTSSLQYCKRNHFLATPTLHSMPSPATKCKPIEPNNN 186
            |||     |.:...:...::::  |:.|.|:|..:       .:.|:.|....|..|.|
Zfish   594 YSN-----STVSTCMTTCKKIAPPPVPPRTTSKPF-------ISVTVQSSTESAQDCYP------ 640

  Fly   187 SNDSSGNFSSGSGHSNGNGSFIKQRVERLYGPGALAQGFYSPKKHGQSPS------NAAGRSERG 245
            ...|.||  |.||.||.:.|....|...| ..|...|...:..:..|.|:      ||...:..
Zfish   641 DRKSDGN--SQSGRSNSSDSLDSTRANSL-AKGTRPQIPVAAPREPQIPAAVVISPNALRETHN- 701

  Fly   246 QVEIDSLQGSELARKFKQLSPSKDYGEFRKKM-----QKKCSQSTTARIDEP-----LHSPGLNG 300
                :.|:|..||.....|.|..     |:|:     |..|.|...|:::.|     ..|.|:..
Zfish   702 ----EPLKGETLAADEPPLEPVP-----RRKLSSIGIQVDCIQEIQAKVETPPPLARFQSIGVQV 757

  Fly   301 DLDLPVFRHLSQEFRAQ------------LPTVSPKRGAPRSCM---------APDVLLVDNESS 344
            :......|..|...|.:            |...|..:.|.:..|         :|.......:|.
Zfish   758 EDGWTFSRSSSMASRQETDSDTQDLSLTSLTFQSGSKSAEQKVMVSCGSQAVDSPPPPPPPQDSD 822

  Fly   345 P---DHGPTDEV-DHESTKMDKLAS-----------------EEYISTSN-----------ISVE 377
            |   ..||:.:: .|.||.....:|                 :.::.:.|           .|..
Zfish   823 PPVSSSGPSRQILTHRSTTQSSSSSFSESLDPALDPSALPPPDPWLESGNGTGNGCSNQPLSSGT 887

  Fly   378 AVVKDGNFFLKILKEEQSRLLVLAALAEKYADALSTNPDISEDTFGLLRSASGKARLLVSQKMKQ 442
            |..:||::|||:|:.|..|:.......||.    :|...:||:..|.:|||.|.|:||::||.:|
Zfish   888 ACRRDGHWFLKLLQAETGRMEGWCCQMEKE----TTEHQLSEEVLGKVRSAVGSAQLLMNQKFQQ 948

  Fly   443 FEGLCHNNLNRSPEDKFPTTLDDLQGFWDMVYLQVEHVDSIFADIEKLKSNDWKVKAQSVADQPD 507
            |.|||..|||.:...:  .|..||.||||::.|.:|.:...|.::..|||||||:..:|...|.:
Zfish   949 FRGLCEQNLNVNANPR--PTAQDLAGFWDLLQLSIEDISLKFDELYHLKSNDWKLNGESPEKQEN 1011

  Fly   508 LHTIPTKTIKPSKVGVSQVKTVGKASSVRVNGSAPPPPNSAAALKREAQRKLLLEMKRQRREAMT 572
            ....|....||.|    ...|:|:..|.          .|....::||:::|:...:.|..:..:
Zfish  1012 QKQAPPVPKKPGK----SKPTLGREKST----------ESVDKQRQEARKRLMAAKRAQSVKQNS 1062

  Fly   573 AAAKLNPINV 582
            |....:.|.:
Zfish  1063 ATESADSIEI 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_001163056.1	GKAP	246..575	CDD:281368	97/391 (25%)
dlgap4b	XP_697562.6	GKAP	720..1081	CDD:281368	92/378 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7559
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000823
OrthoInspector	1	1.000	-	-		otm25339
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12353
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3941
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.900