Protein Alignment vlc and dlgap4a

DIOPT Version :9

• Sequence 1: NP_001163056.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_021325724.1
• Gene: dlgap4a / 562742
• ZFINID: ZDB-GENE-080219-51
• Length: 1034
• Species: Danio rerio
• Alignment Length: 645
• Identity: 161/645 - (24%)
• Similarity: 248/645 - (38%)
• Gaps: 160/645 - (24%)

  Fly     2 DRSLDSI------GSCSL---DVDADSSDISDTSGSLNFPTPVSVRDITREFTANLRERCVP--N 55
            :||||::      |..:|   |||...|....|.|..:..:.|....:.......|..:.|.  :
Zfish   467 NRSLDNLDCLMGPGDAALQHWDVDGGFSQRCATLGRGSIMSQVEQCFMASAAYGQLESQAVEALD 531

  Fly    56 LPPQPQHKTPAYVESRSSELEHMVLSPAIVECDQEPSSNDFDETSAENSQEAPEKKPSYLNLACC 120
            ||      ||....|||    |..|......|.|:      ::|.:.:|.|.|   |...:::.|
Zfish   532 LP------TPTCFRSRS----HSYLRAIQAGCSQD------EDTGSVDSDETP---PITSSISSC 577

  Fly   121 VNGYSNLTTYDSKIRQDINKSREVSPIRPSTSSLQYCKRNHFLATPTLHSMPSPATKCKPIEPNN 185
            .:...:..|...|        :...|:.|..:|..|       .:.|:.|....|.     :...
Zfish   578 NSVTVSTCTAVCK--------KNPPPVPPRNASKPY-------ISVTVQSSTESAQ-----DTYL 622

  Fly   186 NSNDSSGNFSSGSGHSNGNGSFIKQRVERLYGPGALAQGFYSPKKHGQSPSNAAGRSERGQVEID 250
            :|.|.....:|.||.||.:.|....|.      |:|.:|...|......|      :.|..|::.
Zfish   623 DSQDQRSEVNSQSGRSNSSDSLASSRT------GSLVKGSKRPPILPPIP------APREPVQLP 675

  Fly   251 SLQGSELARKFKQLSPSKDYGEFRKKMQKKCSQSTTARIDEP-------LHSPGLNGDLDLPVFR 308
            |.:.:.........:|:.|        .|....|.|...|||       |.|.|:..|...|:
Zfish   676 SARVTTPPPAIAPPTPAPD--------AKPQPLSLTLVPDEPQAPPKRKLSSIGIQVDCVQPI-- 730

  Fly   309 HLSQEFRAQLPT-------VSPKRGAPRS---CMAPDVLLVDNESSP--------DHGPTDEVDH 355
             |.:|   |.||       |..:.|.|.|   .||......:.||..        :..|...:|.
Zfish   731 -LKEE---QTPTTRFQSIGVQVEDGRPLSRFTSMASRQETTEAESQEQSDGKHLGNKTPGQSLDK 791

  Fly   356 ES----TKMDKLASEEYISTS--------------------NISVE-----AVVKDGNFFLKILK 391
            .|    |:....:.:|.:..:                    |.:||     |.::||..|.|:|:
Zfish   792 PSLADMTRSASTSLQEKLDPALDPSRLPPPDPSLQSGSGSVNGAVEQPGGSACLRDGRCFQKLLQ 856

  Fly   392 EEQSRLLVLAALAEKYADALSTNPDISEDTFGLLRSASGKARLLVSQKMKQFEGLCHNNLNRSPE 456
            .|..|:.......|:.    :.:..:||:..|.:|||.|.|:||:|||.:||:|||..||:.|.:
Zfish   857 AETDRMEAWCQQMEEE----TKDKQLSEEVLGKIRSAVGSAQLLMSQKFRQFQGLCEQNLDVSAQ 917

  Fly   457 DKFPTTLDDLQGFWDMVYLQVEHVDSIFADIEKLKSNDWKV--KAQSVADQPDLHTIPTKTIKPS 519
            .:  .|..||.||||::.|.:|.:...|.::..|:|||||.  |.:.....|. || |.||:|..
Zfish   918 PR--PTAQDLAGFWDLLQLSIEDISMKFDELHLLRSNDWKTTDKKEEKKSAPS-HT-PKKTVKVK 978

  Fly   520 KVGVSQVKTVGKASSVRVNGSAPPPPNSAAALKREAQRKLLLEMKR---QRREAMTAAAK 576
            ..|       ||..|:          :|.|..:|:..||.|:..||   :|:.:.|.:|:
Zfish   979 PSG-------GKEKSL----------DSVADKQRQEARKRLMAAKRAVSERQNSATESAE 1021

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_001163056.1	GKAP	246..575	CDD:281368	104/387 (27%)
dlgap4a	XP_021325724.1	GKAP	713..1034	CDD:308780	95/340 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7559
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000823
OrthoInspector	1	1.000	-	-		otm25339
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3941
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.940