Protein Alignment vlc and dlgap3

DIOPT Version :9

• Sequence 1: NP_001163056.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001038179.1
• Gene: dlgap3 / 557556
• ZFINID: ZDB-GENE-060503-413
• Length: 1059
• Species: Danio rerio
• Alignment Length: 726
• Identity: 156/726 - (21%)
• Similarity: 256/726 - (35%)
• Gaps: 233/726 - (32%)

  Fly    16 DADSSDISDTSGSLNFPTPVSVRDITREF---TANLRERCVPNLPPQPQHKTPAYVESRSSELEH 77
            |.||.| ||||..   .:|.|.....||.   :.::.:|.........:..|.||..||::...|
Zfish   387 DDDSVD-SDTSPK---ASPKSALIAQREAFRRSVSMDQRSSTTSKYSCKQCTDAYPNSRTTPKGH 447

  Fly    78 ---MVLSPAIVECDQEPSSNDFD--ETSAENSQEAP----EKKPSYLNL--ACCVNGYSNLTTYD 131
               ...:.::.......:.|.|.  |:.|..:.:.|    .:..||:..  |.|......|:.:.
Zfish   448 ARSRSYTRSLTSAQLGDTLNLFGEMESQAVEALDLPGCFRTRSHSYVRAIQAGCSQDDDCLSVFS 512

  Fly   132 SKIRQDINKSREVSPIR-----------------PSTSSLQYCKRNHFLAT--PTLHSMPSPATK 177
            ..:.|...|...|.|.|                 .:.||.:..:..:|.:|  |.|
Zfish   513 MSVPQASMKGEAVFPYRKGPPPLPPRMSKPMISVTAQSSTESTQDAYFQSTGQPAL--------- 568

  Fly   178 CKPIEPNNNSN-----DSSGNFSSGSGHSNGNGSF-IKQ---RVERLYGPGALAQGFYS-----P 228
               :.|..:||     ::||..:|..||..|.|:. ::|   ..|.|.|....:..::|     .
Zfish   569 ---VRPRQHSNSVDLTENSGGRTSRGGHYLGGGTARVRQSSNSAESLNGRALQSIAYHSGPGPMK 630

  Fly   229 KKHGQSPSN--AAGRSERGQV-------------EIDSLQGSELARKFKQ--------------- 263
            .||..|..|  ...|..|.:|             .:...:...:..:|||
Zfish   631 PKHSSSADNLLEGPRGSRDRVGGSLGKSASLPQNSMSLAKALTVGEEFKQEGRGRKWRPSIAVQV 695

  Fly   264 -----LSPSKDYG--------------EFRKKMQKKCSQSTTARIDEPLHSPGLNGDLDLPV--- 306
                 ||.|...|              :.:::.:.|.|.|.||.:...|.:.|..| |.:|.
Zfish   696 DSSETLSDSDPEGKALREVHSIGVQVEDDKRRARFKRSNSVTASVQADLETEGFGG-LTVPTQDK 759

  Fly   307 --------FRHLSQ------------------------------------EFRAQLP------TV 321
                    .||.|:                                    |.|| ||      .:
Zfish   760 GLQFGCSFQRHSSEPESASQFAEYRTVHTQGQWAYREDYHSGYTTEPGPPELRA-LPRSHSPLPL 823

  Fly   322 SPKRG------APRSCMAPDVLLVDNESSPDHGPTDEVDHESTKMDKLASEEYISTSNISVEAVV 380
            :|:||      .|||.             ||.|                          .....:
Zfish   824 APERGVGGWSEGPRSL-------------PDSG--------------------------RASPCL 849

  Fly   381 KDGNFFLKILKEEQSRLLVLAALAEKYADALSTNPDISEDTFGLLRSASGKARLLVSQKMKQFEG 445
            :||.|||::|:.|..|:.......|:.|:   || ::.|:...|:|.|.|.|::|:||:::||..
Zfish   850 RDGEFFLRLLQTEVERMEGWCQNMEREAE---TN-ELPEEVLELIRGAVGSAQMLMSQRVQQFFR 910

  Fly   446 LCHNNLNRS--PEDKFPTTLDDLQGFWDMVYLQVEHVDSIFADIEKLKSNDWKVKAQSVADQPDL 508
            :|..:::.|  |:   ||| .||..|||::.|.:|.|...|.|:::||.:.|::..:...|:...
Zfish   911 MCQQSVDPSSYPQ---PTT-QDLASFWDLLQLAIEDVRVKFQDLQRLKDSGWRLPPEKKEDKKVP 971

  Fly   509 HTIPTKTIKPSKVGVSQVKTVGKASSVRVNGSAPPPPNSAAAL------KREAQRKLLLEMKRQ- 566
            ..:|.|.| ....|..:..:..::..:.|.......|....:|      |.|.:|: ||:.||.
Zfish   972 PPLPKKPI-GGVTGSLRADSTAESGGMLVVSRGRSLPEREKSLDVGDRQKLETRRR-LLQTKRSA 1034

  Fly   567 --RREAMTAAA 575
              |:.:.|.:|
Zfish  1035 SFRQNSATESA 1045

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_001163056.1	GKAP	246..575	CDD:281368	94/445 (21%)
dlgap3	NP_001038179.1	GKAP	684..1059	CDD:281368	91/413 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7559
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000823
OrthoInspector	1	1.000	-	-		otm25339
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12353
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3941
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.990