Protein Alignment vlc and dlgap5

DIOPT Version :9

• Sequence 1: NP_001163056.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001004592.1
• Gene: dlgap5 / 447853
• ZFINID: ZDB-GENE-040912-160
• Length: 909
• Species: Danio rerio
• Alignment Length: 656
• Identity: 146/656 - (22%)
• Similarity: 245/656 - (37%)
• Gaps: 183/656 - (27%)

  Fly    42 REFTANLRERCVPNLPPQPQHKTPAYVESRSSELE-HMVLSPAIVECDQEPSSNDFDETSAENSQ 105
            ||...|:| |.:..||                |:: .|..|..:...|:.|.:    :|::::|.
Zfish    34 REKIQNMR-RHLDRLP----------------EIDLSMDTSTLMATQDKAPKT----KTASDSSD 77

  Fly   106 EAPEKKPSYLNLACCVNGYSNLTTY-DSKIRQDINKSRE------------------------VS 145
            .|.|:|             ..|..| ::||.|...:.||                        .:
Zfish    78 AAEERK-------------KMLARYKENKILQKEKEKREKEKKGVFKVGLYKPQPLGYLPSNTAA 129

  Fly   146 PIRPSTSSLQYCKR-------NHFLATPTLHSMPSP----ATKCKPIEPNN---NSNDSSGNFSS 196
            |.|...:.:....|       |..||... |::|..    :|...|.:.|.   .|..:....:.
Zfish   130 PGRAKATEMNQSTRMTRSMVQNQKLAVER-HAVPKKVECLSTARAPAKENRKPLTSTKTRATTAE 193

  Fly   197 GSGHSNGNGSFIKQRVERLYGPGALAQGFYSPKKHGQSPSNAAGRSERGQVEIDSLQGSELARKF 261
            ....:....|..|...:.:..|.|..:|   ||........||..|.||:|    :||:..|...
Zfish   194 PPVRAQTTRSAAKTAPDAVVKPVADTRG---PKTRSAVKYPAAPSSGRGKV----VQGNMKANVE 251

  Fly   262 KQLSPSKDYGEFRKKMQKKCSQSTTARIDEPLHSP--------------GLNGDLDLPVF----- 307
            .:.:..||              :...:::||..:|              ||.....:|:.
Zfish   252 NKPAEIKD--------------TAVDKVEEPKAAPASFAPQGFVFQPPVGLRSFEPVPLSPSSAN 302

  Fly   308 RHLSQEFRAQL------PTVSPKRGAPRSCMAPDVLLVDNESSPDH---GPTDEVDHESTKMDKL 363
            ..||..|.:::      |: .||.....|...|.|    :...|||   .|:.....::....:.
Zfish   303 AFLSPSFNSEVSMEPAFPS-PPKPVVSFSSPPPSV----SAHMPDHPISPPSVSSPLQAQSFPQP 362

  Fly   364 ASEEYISTSNISVEAVVKDGNFFLKILKEEQSRLLVLAALAEKYADALSTNPDISEDTFGLLRSA 428
            :::...|.|:.|:|. ..|..:|...:..|..||..|:.|.|...|..|    |.|:....:|:|
Zfish   363 STDAAPSPSSASMEP-QHDVAYFRAAMASETERLTGLSELWESRFDDAS----IPEEMRDRMRTA 422

  Fly   429 SGKARLLVSQKMKQFEGLCHN-NLNRSPEDKFPTTLDDLQGFWDMVYLQVEHVDSIFADIEKLKS 492
            .|:||||:.::..||.||..: :..|.  :|. ||..||||||||||.|||.|:..|:.:::.::
Zfish   423 VGQARLLMKERFGQFNGLVDDCDFKRG--EKI-TTCTDLQGFWDMVYFQVEDVNKKFSALKEAEA 484

  Fly   493 NDWKVKAQSVADQPDLHTIPTKTIKPSKVGVSQVKTVGKASSVRVNGSAPPPPNSAAALKREAQR 557
            .|||.:.:.|..:        :.:|...|      ..|||::    |..    .:|||..|.|..
Zfish   485 RDWKEEVKPVTKK--------RVVKKPPV------VAGKAAA----GGG----GNAAAKSRLAAI 527

  Fly   558 KLLLEMKRQRREAM---------TAAAKLNPI----------NVDADPDVPGIIGDSC----ANP 599
            |..::.|:..::|.         :::..:.|:          .|::....|..:..||    ::|
Zfish   528 KAAMKAKQAEQKATETSDKPQEDSSSVSVAPVQSVVFHGGFFQVESPVKTPAAVRRSCRGVVSSP 592

  Fly   600 SVSNGS 605
            ||:..|
Zfish   593 SVTKFS 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_001163056.1	GKAP	246..575	CDD:281368	89/366 (24%)
dlgap5	NP_001004592.1	GKAP	<360..505	CDD:281368	51/160 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.870