DRSC/TRiP Functional Genomics Resources

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Protein Alignment vlc and IL1RAPL2

DIOPT Version :9

Sequence 1:NP_001163056.1 Gene:vlc / 46078 FlyBaseID:FBgn0259978 Length:605 Species:Drosophila melanogaster
Sequence 2:NP_059112.1 Gene:IL1RAPL2 / 26280 HGNCID:5997 Length:686 Species:Homo sapiens


Alignment Length:182 Identity:42/182 - (23%)
Similarity:70/182 - (38%) Gaps:60/182 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   244 RGQV---EIDSLQGS-ELAR--KFKQLSPSKDYGEF-----------RKKMQKKCSQSTTARIDE 291
            :|:|   |::||:.| :|..  |:|....||...:|           :|:|..:|....:|    
Human   513 KGKVNCQEVESLKRSIKLLSLIKWKGSKSSKLNSKFWKHLVYEMPIKKKEMLPRCHVLDSA---- 573

  Fly   292 PLHSPGLNGDL--------------------DLPVF--------RHLSQEFRAQLPTVS---PKR 325
               ..||.|:|                    |||.|        ||..:.::.::|..:   |..
Human   574 ---EQGLFGELQPIPSIAMTSTSATLVSSQADLPEFHPSDSMQIRHCCRGYKHEIPATTLPVPSL 635

  Fly   326 GAPRS-CMAPDVLLVDNESSPDHGPTDEVD--HESTKMDKLASEEYISTSNI 374
            |...: |..|..||  |...|.:....:..  |.::.:..|:|:|...||:|
Human   636 GNHHTYCNLPLTLL--NGQLPLNNTLKDTQEFHRNSSLLPLSSKELSFTSDI 685

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
vlcNP_001163056.1 GKAP 246..575 CDD:281368 41/180 (23%)
IL1RAPL2NP_059112.1 Ig 32..133 CDD:325142
Ig2_IL1R_like 146..237 CDD:319309
IG_like 250..347 CDD:214653
TIR 402..563 CDD:307630 13/49 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3971
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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