Protein Alignment vlc and Dlgap2

DIOPT Version :9

• Sequence 1: NP_001163056.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001139437.1
• Gene: Dlgap2 / 244310
• MGIID: 2443181
• Length: 1060
• Species: Mus musculus
• Alignment Length: 670
• Identity: 159/670 - (23%)
• Similarity: 245/670 - (36%)
• Gaps: 183/670 - (27%)

  Fly    16 DADSSDISDTSGSLNFPT----------PVSVRDI----TREFTANLRERCVP---NLPPQPQHK 63
            |.:|.: ||:|...: ||          |:..|.:    |:.:.....|  ||   :|.|...:.
Mouse   448 DEESGE-SDSSPKTS-PTVAIRPEPLLKPIIQRPLGDHQTQSYLQAATE--VPVGHSLNPSINYN 508

  Fly    64 TPAYVESRSSELEHMVLSPAIVECDQEPS----SNDFDETSAENSQEAPEKKPSYLNLACC--VN 122
            :|.: .||:......|.:.:...|..:.|    :..|:........|...:....|:|..|  ..
Mouse   509 SPKF-RSRNQSYMRAVSTLSQASCVSQMSEAEVNGQFESVCESVFSEVESQAMDALDLPGCFRTR 572

  Fly   123 GYSNLTTYDSKIRQD------INKSREVSPIRPSTSSLQYCKRNHFLATPTLHSMPSPATKCKPI 181
            .:|.|....:...||      :..|...|.|| ||:::.|   .::..||.  .:| |.|..||:
Mouse   573 SHSYLRAIQAGYSQDDECIPVMTSSNMTSTIR-STAAVSY---TNYKKTPP--PVP-PRTTSKPL 630

  Fly   182 -----EPNNNSNDSSGNFS-----------SGSGHSNGNGSFIKQRVERLYGPGALAQGFYSPKK 230
                 :.:..|...:...|           |..|..|...|....:...|....|.||      :
Mouse   631 ISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGGLYNSMDSLDSNKAMNLALETAAAQ------R 689

  Fly   231 HGQSPSNAAGRS----------------------------------ERGQVE--IDSLQGSELAR 259
            |.....:::.||                                  .|..||  .||...|...|
Mouse   690 HAADTQSSSTRSIDKAVLASKAEELLKSRCSSIGVQDSEFPDHQPYPRSDVETATDSDTESRGLR 754

  Fly   260 KFK----QLSPSKDYGEFRKKMQKKCSQSTTARIDEPLHSPGLNGDLDLPVFRHLSQE------- 313
            ::.    |:...|.:|.|::      |.|.||.:...|...|..|        |:|.|
Mouse   755 EYHSVGVQVEDEKRHGRFKR------SNSVTAAVQADLELEGFPG--------HVSMEDKGLQFG 805

  Fly   314 ---FRAQLPTVSPKRGAPRSCMAPDVL--------LVDNESSPDHGPTDEVDHESTKMDKLASEE 367
               .|...|:...:.||.|:.....:.        .||..:.|...|..|           .|.:
Mouse   806 SSFQRHSEPSTPTQYGALRTVRTQGLFSYREDYRTQVDTSTLPPPDPWLE-----------PSLD 859

  Fly   368 YISTSNISVEAVVKDGNFFLKILKEEQSRLLVLAALAEKYADALSTNPDISEDTFGLLRSASGKA 432
            .:.|..:|  ...:||::|||:|..|..|:.......|:.|:    ..|:.||..|.:|||.|.|
Mouse   860 TVETGRMS--PCRRDGSWFLKLLHTETKRMEGWCKEMEREAE----ENDLLEDILGKIRSAVGSA 918

  Fly   433 RLLVSQKMKQFEGLCHNNLNRSPEDKFPTTLDDLQGFWDMVYLQVEHVDSIFADIEKLKSNDWKV 497
            :||:|||.:||..||..|::.|...: ||: .||.|:|||:.|.||.|...|.::.:||.||||:
Mouse   919 QLLMSQKFQQFYWLCQQNMDPSAMPR-PTS-QDLAGYWDMLQLSVEDVSMKFDELHQLKLNDWKI 981

  Fly   498 ------KAQSVADQPDLHTIPTKTIKPSKVGVSQVKTVG-----------------KASSVRVNG 539
                  |.:.....|    ||.|..| .|..:::.|::.                 :|:|.|.|
Mouse   982 IESPERKEERKIPPP----IPKKPPK-GKFPITREKSLDLPDRQRQEARRRLMAAKRAASFRQN- 1040

  Fly   540 SAPPPPNSAAALKREAQRKL 559
            ||....:|......|||.:|
Mouse  1041 SATERADSIEIYIPEAQTRL 1060

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_001163056.1	GKAP	246..575	CDD:281368	101/361 (28%)
Dlgap2	NP_001139437.1	GKAP	716..1060	CDD:281368	101/382 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000823
OrthoInspector	1	1.000	-	-		otm43106
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12353
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3941
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.990