Protein Alignment vlc and Dlgap1

DIOPT Version :9

• Sequence 1: NP_001163056.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_006524231.1
• Gene: Dlgap1 / 224997
• MGIID: 1346065
• Length: 1030
• Species: Mus musculus
• Alignment Length: 668
• Identity: 141/668 - (21%)
• Similarity: 237/668 - (35%)
• Gaps: 202/668 - (30%)

  Fly     1 MDRSLDSIGSCSLDVDADSSDISDTSGSLNFP----------------TPVSVRDITREFTANLR 49
            ::|||||:               |.:|.|..|                :.||..::..:|
Mouse   460 INRSLDSL---------------DPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQF----- 504

  Fly    50 ERCVPNLPPQPQHKTPAYVESRSSELEHMVL--------------SPAIVECDQEPSSNDFDETS 100
                           .:..||..||||...:              |.:.|...::..|.| ||..
Mouse   505 ---------------ESVCESVFSELESQAVEALDLPLPGCFRMRSHSYVRAIEKGCSQD-DECV 553

  Fly   101 AENSQEAP---------EKKPSYLNLACCVNGYSNLTTYDSKIRQDINKSREVSPIRPSTSSLQY 156
            :..|...|         :.....:.|:..|...|.:|||          .:...|:.|.|::
Mouse   554 SLRSSSPPRTTTTVRTIQSSTGVIKLSSAVEVSSCITTY----------KKTPPPVPPRTTT--- 605

  Fly   157 CKRNHFLATPTLHSMPSPATKCKPIEPNNNSNDSSGNFSSGSGHSNGNGSF---------IKQRV 212
               ..|::.....|..|..      :...:.....|:..|.||.||...|.         |:...
Mouse   606 ---KPFISITAQSSTESAQ------DAYMDGQGQRGDMISQSGLSNSTESLDSMKALTAAIEAAN 661

  Fly   213 ERLYGPGALAQGFYSPKKHGQSPSNAAGRSERGQV----------------------------EI 249
            .:::||.:...|           ||||..:....:                            |.
Mouse   662 AQIHGPASQHMG-----------SNAAAVTTTTTIATVTTEDRKKDFKKNRCLSIGIQVDDAEEP 715

  Fly   250 DSLQGSELARKFKQLSPSKDYGEFRKKMQKKCSQSTTARIDEPLHSPGLNGDLDL--------PV 306
            :.:..|:.:.||:.:....:..:..::..:..|.:|..:.|...|. .|...|:.        |:
Mouse   716 EKMAESKTSNKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHD-NLENSLESIEDNSCPGPM 779

  Fly   307 FRHLSQEFRAQLPTVSPKRGAPRSCMAPDVLLVDNESSPDHGPTDEVDHESTKMDKLASEEYIST 371
            .|..|::......::........:|.|.|..  |.:..|...|..:...:|...|.|
Mouse   780 ARQFSRDASTSTVSIQGSGNHYHACAADDDF--DTDFDPSILPPPDPWIDSITEDPL-------- 834

  Fly   372 SNISVEAVV-----KDGNFFLKILKEEQSRLLVLAALAEKYADALSTNPDISEDTFGLLRSASGK 431
                 |||.     :||::|||:|:.|:.|:.....|.|:.    ....::.||..|.:|:|.|.
Mouse   835 -----EAVQRSVCHRDGHWFLKLLQAERDRMEGWCKLMERE----ERENNLPEDILGKIRTAVGS 890

  Fly   432 ARLLVSQKMKQFEGLCHNNLNRSPEDKFPTTLDDLQGFWDMVYLQVEHVDSIFADIEKLKSNDWK 496
            |:||::||..||..||..|||.:...: ||: .||.|||||:.|.:|::...|.::.:||:|:|
Mouse   891 AQLLMAQKFYQFRELCEENLNPNAHPR-PTS-QDLAGFWDMLQLSIENISMKFDELHQLKANNW- 952

  Fly   497 VKAQSVADQPDLHTIPTKTIKPSKVGVSQVKTVGKASSVRVNGSAPPPPNSAAALKREAQRKLLL 561
             |.....|:.:....|....||:|         |.|..:|        ..|..:.:|:..||.|:
Mouse   953 -KQMDPLDKKERRAPPPVPKKPAK---------GPAPLIR--------ERSLESSQRQEARKRLM 999

  Fly   562 EMKRQ---RREAMTAAAK 576
            ..||.   |:.:.|.:|:
Mouse  1000 AAKRAASVRQNSATESAE 1017

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_001163056.1	GKAP	246..575	CDD:281368	87/372 (23%)
Dlgap1	XP_006524231.1	GKAP	698..1030	CDD:367461	88/361 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000823
OrthoInspector	1	1.000	-	-		otm43106
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12353
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3941
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.990