Protein Alignment vlc and Dlgap5

DIOPT Version :9

• Sequence 1: NP_001163056.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_006518898.1
• Gene: Dlgap5 / 218977
• MGIID: 2183453
• Length: 820
• Species: Mus musculus
• Alignment Length: 569
• Identity: 130/569 - (22%)
• Similarity: 212/569 - (37%)
• Gaps: 144/569 - (25%)

  Fly    31 FP-TPVSVRDITREF--TANLRERCVPNLPPQPQHKTPAYVESRSSELEHMVLSPAIVECDQEPS 92
            || |....|..|:|:  ...:..|.||......|.:|.   |.:..:.|..|:.|.:.
Mouse   145 FPHTGRITRSKTKEYMEQTKIGSRNVPKATQSDQRQTS---EKQPLDRERKVMQPVLF------- 199

  Fly    93 SNDFDETSAENSQEAPEKKPSYLNLACCVNGYSNLTTYDSKIRQDINKS---REVSPIRPSTSSL 154
                  ||.:.::.|..::...:           ..|..|..|:.:.::   :....:|||
Mouse   200 ------TSGKGTESAATQRAKLM-----------ARTVSSTTRKPVTRATNEKGSERMRPS---- 243

  Fly   155 QYCKRNHFLATPTLHSMPSPATKCKP-------IEPNNNSNDSSGNFSSGSGHSNGNGSFIKQRV 212
                          ...|:...:.||       :|.:....||....:|..|..   |.|  :.|
Mouse   244 --------------GGRPAKKPEGKPDKVIPSKVERDEKHLDSQTRETSEMGPL---GVF--REV 289

  Fly   213 ERLYGPG-ALAQGFYSPKKHGQSPSNAAGRSERGQVEIDSLQGSELARKFKQ--LSPSKDYGEFR 274
            |.|  |. |.|||   .::...:|.:...:...|   :.|.|.:.|:.:...  |:|:.|:.:.|
Mouse   290 ESL--PATAPAQG---KERKSFAPKHCVFQPPCG---LKSYQVAPLSPRSANAFLTPNCDWNQLR 346

  Fly   275 KKMQKKCSQSTTARIDEPLHSPGLNGDLDLPVFRHLSQEFRAQLPTVSPKRGAPRSCMAPDVLLV 339
            .::   .|.:|..:.:|.|...||....|......|:|            :||..|        .
Mouse   347 PEV---FSTTTQDKANEILVQQGLESLTDRSKEHVLNQ------------KGASTS--------D 388

  Fly   340 DNESSPDHGPTDEVDHESTKMDKLASEEYISTSNISVEAVVKDGNFFLKILKEEQSRLLVLAALA 404
            .|.:|....|..|.....|....                  .|..:|.|||:.|..|   |.:..
Mouse   389 SNHASVKGVPCSEASEGQTSQPP------------------HDVPYFRKILQSETDR---LTSHC 432

  Fly   405 EKYADALSTNPDISEDTFGLLRSASGKARLLVSQKMKQFEGLCHNNLNRSPEDKFPTTLDDLQGF 469
            :::...|..  ||.::..||:|:..|:.|||:.::.:|||||..|...:..|.:  ||..||.||
Mouse   433 QEWEGKLDL--DIPDEAKGLIRTTVGQTRLLIKERFRQFEGLVDNCEYKRGEKE--TTCTDLDGF 493

  Fly   470 WDMVYLQVEHVDSIFADIEKLKSNDWKVKAQSVADQPDLHTIPTKTIKPSKVGVSQVKTVGKASS 534
            ||||..||:.|:..|.::.||:::.||          |.:. |:|.:...|:      ..|:.|.
Mouse   494 WDMVSFQVDDVNQKFNNLIKLEASGWK----------DSNN-PSKKVLRKKI------VPGRTSK 541

  Fly   535 VRVNGSAPPPPNSAAALKREAQRKLLLEMKRQRREAMTAAAKLNPINVD 583
            .:.:..     ..|||..|.|..|..::.:.|:.....|||..|...||
Mouse   542 AKQDDD-----GRAAARSRLAAIKNAMKGRPQQEVQAHAAAPENTKEVD 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_001163056.1	GKAP	246..575	CDD:281368	81/330 (25%)
Dlgap5	XP_006518898.1	GKAP	<399..543	CDD:367461	51/185 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870