Protein Alignment vlc and W03A5.6

DIOPT Version :9

• Sequence 1: NP_001163056.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001337304.1
• Gene: W03A5.6 / 189142
• WormBaseID: WBGene00020970
• Length: 612
• Species: Caenorhabditis elegans
• Alignment Length: 624
• Identity: 143/624 - (22%)
• Similarity: 226/624 - (36%)
• Gaps: 194/624 - (31%)

  Fly     3 RSLDSIGSCSLDVDADSSDISDTSGSLNFPTPVSVRDITREFTANLRERCVPNLPPQP------- 60
            ||..|.|:.:..::..|:..||...:|                          |||:|
 Worm   107 RSSSSRGASTDSLNTTSNGFSDGGSNL--------------------------LPPKPNRIGCAA 145

  Fly    61 ---QHKTP-AYVESRSSELEHMVLSPAIVECDQEP----SSNDFDETSAENSQEAPE--KKPSYL 115
               |.:|. .:|.||.:. ..:.|:......::.|    |.||....:|..|.:.||  :.||||
 Worm   146 TGAQSETDLRFVTSRDTH-SSIPLNEPFGFGEKSPRAFMSENDLSAGAAGASTDFPEVTRTPSYL 209

  Fly   116 NLACCVNGYSNLTTYDSKIRQDINKSREVSPIRP----STSSLQYCKRNHFLATPTLHSMPSPAT 176
            .::|.:|||:          :..||| :::||.|    ||....:.:|...:.:......|:|..
 Worm   210 RISCALNGYT----------KSPNKS-DLTPIAPHPPVSTMGESFVERRSRMFSQPQQRNPAPGF 263

  Fly   177 KCKPIEPNNNSNDSSGNFSSGS--------------GHSN--GNGSFIKQRVERLYGPGALAQGF 225
            . .|:.|...|:.|:.:....|              .|::  ||.:.|.|.:..|.
 Worm   264 S-SPLPPTTVSSQSASSEIECSTPIVPLKNARLNTLQHTSEMGNHASIPQPIRDLI--------- 318

  Fly   226 YSPKKHGQSPSNAAGRSERGQVE-------IDSLQGSELARKFKQLSPSKD-YGEFRKKMQKKCS 282
               .|..|....:|.::|:..:|       |.:.|.:     |.::...|| .|...:|...|.|
 Worm   319 ---SKFNQLDLCSAHKNEKEGIENIEPHKFIINQQPA-----FDEIDLKKDSNGNDDEKKDLKIS 375

  Fly   283 QSTTARIDEPLHSPGLNGDLDLPVFRHLSQEFRAQLPTVSPKRGAPRSCMAPDVLLVDNESSPDH 347
                  ||....| |::|                                          |||..
 Worm   376 ------IDAESDS-GISG------------------------------------------SSPAS 391

  Fly   348 GPTD-EVDHESTKMDKLASEEYISTSNISVEAVVKDGNFFLKILKEEQSRLLVLAALAEKYADAL 411
            ...: ::..|..|.|:  .||..:||..|      :|:.| ::|.::     |.|.|..| .:|.
 Worm   392 SKKNIDISKEEPKQDE--EEEVTTTSTPS------NGHEF-QLLHDK-----VKAQLQTK-MNAA 441

  Fly   412 STN----PDISEDTFGLLRSASGKARLLVSQKMKQFEGLCHNNLNRSPEDKFPTTLDDLQGFWDM 472
            ||:    .|..|.....||:|.|.|.|||.:|..:|..|...|||...:|..|.|:.||:|||..
 Worm   442 STDLEHADDYPEKCSDSLRAAHGNAHLLVRKKFSKFNELIGKNLNPIADDPMPVTVQDLEGFWVT 506

  Fly   473 VYLQVEHVDSIFADIEKLKSNDWKVKAQSVADQPDLHTIPTKTIKPSKVGVSQVKTVGKASSVRV 537
            :.::::.:...|..:|:.::.:|...|....::.| .|.....|.|            |...|..
 Worm   507 IDMELKGILKEFTKVEQYRAANWDPSAVKEEEEID-STTNRPPIAP------------KTRPVTA 558

  Fly   538 NGSAPPPPNSAAALKREAQRKLLLEMK---RQRREAMTA 573
            ...||        :..|..||.|.|.|   .|||..|.|
 Worm   559 KKKAP--------IVSEETRKKLAEQKALAEQRRAEMRA 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_001163056.1	GKAP	246..575	CDD:281368	83/344 (24%)
W03A5.6	NP_001337304.1	GKAP	<446..588	CDD:308780	45/162 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I3595
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14719
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12353
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3941
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.180