Protein Alignment vlc and Dlgap2

DIOPT Version :9

• Sequence 1: NP_001163056.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_038950082.1
• Gene: Dlgap2 / 116681
• RGDID: 620224
• Length: 1060
• Species: Rattus norvegicus
• Alignment Length: 665
• Identity: 157/665 - (23%)
• Similarity: 246/665 - (36%)
• Gaps: 178/665 - (26%)

  Fly    16 DADSSDISDTSGSLNFPTPVSVRDI---------TREFTANLRERCVP---NLPPQPQHKTPAYV 68
            ::|||..:..:.:|. |.|: ::.|         |:.:.....|  ||   :|.|...:.:|.:
  Rat   453 ESDSSPKTSPTVALR-PEPL-LKSIIQRPLGDHQTQSYLQAATE--VPVGHSLDPSVNYNSPKF- 512

  Fly    69 ESRSSELEHMVLSPAIVECDQEPS----SNDFDETSAENSQEAPEKKPSYLNLACC--VNGYSNL 127
            .||:......|.:.:...|..:.|    :..|:........|...:....|:|..|  ...:|.|
  Rat   513 RSRNQSYMRAVSTLSQASCVSQMSEAEVNGQFESVCESVFSEVESQAMDALDLPGCFRTRSHSYL 577

  Fly   128 TTYDSKIRQD------INKSREVSPIRPSTSSLQYCKRNHFLATPTLHSMPSPATKCKPI----- 181
            ....:...||      :..|...|.|| ||:::.|   .::..||.  .:| |.|..||:
  Rat   578 RAIQAGYSQDDECIPVMTPSNMTSTIR-STAAVSY---TNYKKTPP--PVP-PRTTSKPLISVTA 635

  Fly   182 EPNNNSNDSSGNFS-----------SGSGHSNGNGSFIKQRVERLYGPGALAQGFYSPKKHGQSP 235
            :.:..|...:...|           |..|..|...|....:...|....|.||      :|....
  Rat   636 QSSTESTQDAYQDSRAQRMSPWPQDSRGGLYNSMDSLDSNKAMNLALESAAAQ------RHAADT 694

  Fly   236 SNAAGRS----------------------------------ERGQVE--IDSLQGSELARKFK-- 262
            .:::.||                                  .|..||  .||...|...|::.
  Rat   695 QSSSTRSIDKAVLVSKAEELLKSRCSSIGVQDSEFPDHQPYPRSDVETATDSDTESRGLREYHSV 759

  Fly   263 --QLSPSKDYGEFRKKMQKKCSQSTTARIDEPLHSPGLNGDLDLPVFRHLSQE----------FR 315
              |:...|.:|.|::      |.|.||.:...|...|..|        |:|.|          .|
  Rat   760 GVQVEDEKRHGRFKR------SNSVTAAVQADLELEGFPG--------HVSMEDKGLQFGSSFQR 810

  Fly   316 AQLPTVSPKRGAPRSCMAPDVL--------LVDNESSPDHGPTDEVDHESTKMDKLASEEYISTS 372
            ...|:...:.||.|:.....:.        .||..:.|...|..|           .|.:.:.|.
  Rat   811 HSEPSTPTQYGALRTVRTQGLFSYREDYRTQVDTSTLPPPDPWLE-----------PSLDTVETG 864

  Fly   373 NISVEAVVKDGNFFLKILKEEQSRLLVLAALAEKYADALSTNPDISEDTFGLLRSASGKARLLVS 437
            .:|  ...:||::|||:|..|..|:.......|:.|:    ..|:||:..|.:|||.|.|:||:|
  Rat   865 RMS--PCRRDGSWFLKLLHTETKRMEGWCKEMEREAE----ENDLSEEILGKIRSAVGSAQLLMS 923

  Fly   438 QKMKQFEGLCHNNLNRSPEDKFPTTLDDLQGFWDMVYLQVEHVDSIFADIEKLKSNDWKV----- 497
            ||.:||..||..|::.|...: ||: .||.|:|||:.|.||.|...|.::.:||.||||:
  Rat   924 QKFQQFYWLCQQNMDPSAMPR-PTS-QDLAGYWDMLQLSVEDVSMKFDELHQLKLNDWKIMESPE 986

  Fly   498 -KAQSVADQPDLHTIPTKTIKPSKVGVSQVKTVG-----------------KASSVRVNGSAPPP 544
             |.:.....|    ||.|..| .|..:::.|::.                 :|:|.|.| ||...
  Rat   987 RKEERKIPPP----IPKKPPK-GKFPITREKSLDLPDRQRQEARRRLMAAKRAASFRQN-SATER 1045

  Fly   545 PNSAAALKREAQRKL 559
            .:|......|||.:|
  Rat  1046 ADSIEIYIPEAQTRL 1060

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_001163056.1	GKAP	246..575	CDD:281368	101/361 (28%)
Dlgap2	XP_038950082.1	GKAP	716..1060	CDD:397439	101/382 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000823
OrthoInspector	1	1.000	-	-		otm45172
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12353
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.960