Protein Alignment vlc and dlgap2

DIOPT Version :10

• Sequence 1: NP_524868.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_031758364.1
• Gene: dlgap2 / 100489352
• XenbaseID: XB-GENE-986275
• Length: 1018
• Species: Xenopus tropicalis
• Alignment Length: 654
• Identity: 157/654 - (24%)
• Similarity: 241/654 - (36%)
• Gaps: 163/654 - (24%)

  Fly     9 GSCSLDVDADSSDISDTSGSLN-----FPTPV-------SVRDITREFTANLRERCVPN--LPPQ 59
            ||....::.||.| ||||...:     .|.|:       |..::..:..........|.  |.|.
 Frog   395 GSYIKAMEEDSGD-SDTSPKTSPKISPRPEPLLKSVGQRSHVEVQNQSYLQAASEMPPGHILDPS 458

  Fly    60 PQHKTPAYVESRSSELEHMVLSPAIVECDQEPSSNDFDETSAE---NSQEAPEKKPS-------- 113
            ..:.:|.: .||:......|.:.:...|    .|.||...|.:   .|:|.||.|.:
 Frog   459 GNYNSPKF-RSRNQSYMRAVSTLSQASC----VSQDFLIESLQECFTSKEYPEIKMAETEINGQY 518

  Fly   114 -----------------YLNLACC--VNGYSNLTTYDSKIRQD------INKSREVSPIRPSTSS 153
                             .|:|..|  ...:|.|....:...||      |..|...|..| ||::
 Frog   519 ESVNESVFSEMDSHAVDALDLPGCFRTRSHSYLRAIQAGYSQDDDCIPAITTSNVTSSTR-STTA 582

  Fly   154 LQYCKRNHFLATPTLHSMPSPATKCKPI-----EPNNNSNDSSGNFS----------SGSGHSNG 203
            ..|.   ::..||.  .:| |.|..||:     :.:..|...:.:.|          .|.|..|.
 Frog   583 ATYA---NYKKTPP--PVP-PRTTSKPLISVTAQSSTESTQDAYHDSRTQRISPWPHDGRGLYNS 641

  Fly   204 NGSFIKQRVERLYGPGALAQGFYSPKKHG--QSPSNAA------------GRSERG-QVE-IDSL 252
            ..|....:...|....|.|....|..|..  :|.|:.|            .||..| ||| .||.
 Frog   642 TDSLDSNKAMNLALESAAAHRHVSEIKSSSVKSTSDKAVLVTKSDDFLKKRRSSIGIQVEAADSD 706

  Fly   253 QGSELARKFK----QLSPSKDYGEFRKKMQKKCSQSTTARIDEPLHSPGLNGDLDLPVFRHLSQE 313
            ..|:..|::.    |:...|..|.|::      |.|.||.:...|...|..|        |::.|
 Frog   707 SESKGHREYHSVGVQVEDEKRQGRFKR------SNSVTAAVQADLELEGFPG--------HVTME 757

  Fly   314 ----------FRAQLPTVSPKRGAPRSCMA-------PDVLLVDNESSPDHGPTDEVDHESTKMD 361
                      .|...|:...:.||.|:...       .|..:.|..:.|...|..|..||:....
 Frog   758 DKGLQFGSSFQRHSEPSTPTQYGAVRTVRTQGLFSYREDYRMPDTSNLPPPDPWLEPSHEAVDSG 822

  Fly   362 KLASEEYISTSNISVEAVVKDGNFFLKILKEEQSRLLVLAALAEKYADALSTNPDISEDTFGLLR 426
            :::...             :||.:|:|:|..|..|:.......|:.|:    ..|::|:..|.:|
 Frog   823 RISPSR-------------QDGTWFMKLLHAETKRMEEWCKDMEREAE----ENDLTEENLGKIR 870

  Fly   427 SASGKARLLVSQKMKQFEGLCHNNLNRSPEDKFPTTLDDLQGFWDMVYLQVEHVDSIFADIEKLK 491
            ||.|.|:||:|||.:||..||..|::.|...: ||: .||.||||::.|.:|.|...|..:.:||
 Frog   871 SAVGSAQLLMSQKFQQFYWLCQQNMDPSAMPR-PTS-QDLAGFWDLLQLSIEDVSMKFDKLHQLK 933

  Fly   492 SNDWKVKAQSVADQPDLHTIPTKTIKPSKVGVSQVKTVGKASSVRVNGSAPPPPNSAAALKREAQ 556
            :|:||     ..|.|:     .|..|...:.:.:..|.||....|......|...     ::||:
 Frog   934 ANEWK-----AVDSPE-----KKDDKKLPLPIPKKPTRGKFPITREKSLDLPDRQ-----RQEAR 983

  Fly   557 RKLL 560
            |:|:
 Frog   984 RRLM 987

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_524868.1	GKAP	<381..>496	CDD:460897	43/114 (38%)
dlgap2	XP_031758364.1	GKAP	690..1018	CDD:460897	93/346 (27%)