DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vlc and il1rapl2

DIOPT Version :9

Sequence 1:	NP_001163056.1	Gene:	vlc / 46078	FlyBaseID:	FBgn0259978	Length:	605	Species:	Drosophila melanogaster
Sequence 2:	NP_001136056.1	Gene:	il1rapl2 / 100149452	ZFINID:	ZDB-GENE-040219-5	Length:	681	Species:	Danio rerio

Alignment Length:	293	Identity:	54/293 - (18%)
Similarity:	106/293 - (36%)	Gaps:	102/293 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 CMAPDVLLVDNESSPDHGPTDEVDHESTKMDKLASEEYISTSNISVEAVVKDGNFFLKILKEEQS 395
            |...:::|...:    |..:||.|..:.:.|     .|:|.:.:.:::|.::      :.:|||.
Zfish   376 CYNVEIMLCYRQ----HFGSDEADDGNKEYD-----AYLSYTKVDLDSVEQE------MSEEEQF 425

  Fly   396 RLLVLAALAEK---------YADALSTNPDISEDTFGLLRSASGKARLLV----------SQKMK 441
            .|.:|..:.||         :.|.:.::..|.:    |.||.....||::          ...:.
Zfish   426 ALEILPDVLEKHYGYKLFIPHRDLIPSSTYIED----LARSVEQSRRLIIVLTPEFVARRGWSIF 486

  Fly   442 QFEGLCHNNLNRSPEDKFPTTLDDLQGFWDMVYLQVEHVDSI--FADIEKLKSNDWKVKAQSVAD 504
            |||...|:.|              :.|...::.::...:.|:  :.::|.||
Zfish   487 QFEPRLHSML--------------VTGEIKVIMIECPDLRSVINYQEVEDLK------------- 524

  Fly   505 QPDLHTIPTKTIKPSKVGVSQVKTVGKASSVRVNGSAPPPPNSAAALKREAQRKLLLEMKRQRRE 569
                |||...|:         :|..|..|:               .||.:..:::..||..:::|
Zfish   525 ----HTIRVLTL---------IKWQGPKSN---------------QLKSKFWKQVRYEMPAKKKE 561

  Fly   570 AMTAAAKLNPINVDADPDVPGIIGDSCANPSVS 602
            .|:....|       |....|:.||..|..:|:
Zfish   562 TMSRRQVL-------DSGEQGLFGDLQAVSTVA 587

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_001163056.1	GKAP	246..575	CDD:281368	47/264 (18%)
il1rapl2	NP_001136056.1	Ig	32..133	CDD:299845
		IG_like	39..133	CDD:214653
		Ig	146..232	CDD:299845
		IG_like	160..231	CDD:214653
		I-set	247..347	CDD:254352
		Ig	253..347	CDD:299845
		TIR	400..558	CDD:214587	39/227 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900