Protein Alignment Acsl and FAA3

DIOPT Version :9

• Sequence 1: NP_001260810.1
• Gene: Acsl / 46068
• FlyBaseID: FBgn0263120
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_012257.1
• Gene: FAA3 / 854808
• SGDID: S000001271
• Length: 694
• Species: Saccharomyces cerevisiae
• Alignment Length: 693
• Identity: 234/693 - (33%)
• Similarity: 345/693 - (49%)
• Gaps: 68/693 - (9%)

  Fly    82 TDPPRDVHVKM------LQENIDTLE----KVFNY-----------VAKTYTSKRCLGTRQILSE 125
            |.|.|:|.||.      |..:..||.    :.||.           |.:.:.:|:.: .|::..:
Yeast    18 TAPRRNVRVKKRPLIRPLNSSASTLYEFALECFNKGGKRDGMAWRDVIEIHETKKTI-VRKVDGK 81

  Fly   126 EDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELGQKP--RENIVIFAETRAEWMIAA 188
            :..::   :.:..|.:..||..|:.|......:.||||.::|.||  .....|||.|..:||...
Yeast    82 DKSIE---KTWLYYEMSPYKMMTYQELIWVMHDMGRGLAKIGIKPNGEHKFHIFASTSHKWMKIF 143

  Fly   189 HGCFKQAMPIVTVYATLGDDGVAHCITETEVTTVITSHDLLPKFKTLLDKCPLVKTIIYIE---- 249
            .||..|.:|:||.|.|||:.|:.|.:.|||...:.|.:.||.|....|.....:|.:|:.|
Yeast   144 LGCISQGIPVVTAYDTLGESGLIHSMVETESAAIFTDNQLLAKMIVPLQSAKDIKFLIHNEPIDP 208

  Fly   250 --------------DQLQKTETTGFKEGVKILPFNQVVKTGQDSKFE---HVPPKGDDIAIIMYT 297
                          |.:.|....  :..:||..|.:|||.|:.||.|   | ||:..|:|.||||
Yeast   209 NDRRQNGKLYKAAKDAINKIREV--RPDIKIYSFEEVVKIGKKSKDEVKLH-PPEPKDLACIMYT 270

  Fly   298 SGSTGTPKGVLLSHKNCIATMKGFVDMV--PIYPDDVLIGFLPLAHVFELVAESVCLMTGVPIGY 360
            |||...||||:|:|.|.::.:.|....|  .|...|.::.||||||:||||.|.........:||
Yeast   271 SGSISAPKGVVLTHYNIVSGIAGVGHNVFGWIGSTDRVLSFLPLAHIFELVFEFEAFYWNGILGY 335

  Fly   361 STPLTLIDTSSKIKRGCKGDATVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYK 425
            .:..||.:||:   |.||||....|||.|..|..:.:.:.|.|.:|::..:...:.:|...|..|
Yeast   336 GSVKTLTNTST---RNCKGDLVEFKPTIMIGVAAVWETVRKAILEKISDLTPVLQKIFWSAYSMK 397

  Fly   426 VKWVQRGYKTPLIDKLVFKKVAKLMGGKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETT 490
            .|.|.   .|..:.::|||||.:..||.::.||:||:.:|.|..:.....|| .:|.|||||||.
Yeast   398 EKSVP---CTGFLSRMVFKKVRQATGGHLKYIMNGGSAISIDAQKFFSIVLC-PMIIGYGLTETV 458

  Fly   491 SGATVMDYRDMTYGRTGGPLTVCDIRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKT 555
            :.|.|::.....||..|..:.....:||:.::..|...|.   |||:|:.|..|...|||.|.:|
Yeast   459 ANACVLEPDHFEYGIVGDLVGSVTAKLVDVKDLGYYAKNN---QGELLLKGAPVCSEYYKNPIET 520

  Fly   556 NEDFFEEDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICV 620
            ... |..||  ||:||||.|....|.||||||:|:|||...|||::|.|:||..::...::||||
Yeast   521 AVS-FTYDG--WFRTGDIVEWTPKGQLKIIDRRKNLVKTLNGEYIALEKLESVYRSNSYVKNICV 582

  Fly   621 YGDPTKQYTVALVVPNQNHLEELAQKHGLGDK--SFEELCSSPIIEKAILKEIAEHARKCKLQKY 683
            |.|.::...|.:||||...|.:.|.|..:..|  ..|.......:..|:.||:...|:...|...
Yeast   583 YADESRVKPVGIVVPNPGPLSKFAVKLRIMKKGEDIENYIHDKALRNAVFKEMIATAKSQGLVGI 647

  Fly   684 EVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDINRMY 726
            |:...|....|.|:|:.|.||:|.||||::|....:.::.|:|
Yeast   648 ELLCGIVFFDEEWTPENGFVTSAQKLKRREILAAVKSEVERVY 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsl	NP_001260810.1	PLN02387	95..727	CDD:215217	227/674 (34%)
		LC-FACS_euk	142..726	CDD:213293	218/610 (36%)
FAA3	NP_012257.1	LC_FACS_euk1	95..678	CDD:341294	216/598 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343796
Domainoid	1	1.000	260	1.000	Domainoid score	I309
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	341	1.000	Inparanoid score	I409
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53493
OrthoFinder	1	1.000	-	-		FOG0001203
OrthoInspector	1	1.000	-	-		otm46492
orthoMCL	1	0.900	-	-		OOG6_100746
Panther	1	1.100	-	-	O	PTHR43272
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R654
SonicParanoid	1	1.000	-	-		X593
TreeFam	1	0.960	-	-
	14	13.790