DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Acsl and LACS6

DIOPT Version :9

Sequence 1:	NP_001260810.1	Gene:	Acsl / 46068	FlyBaseID:	FBgn0263120	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	NP_566265.1	Gene:	LACS6 / 819767	AraportID:	AT3G05970	Length:	701	Species:	Arabidopsis thaliana

Alignment Length:	736	Identity:	226/736 - (30%)
Similarity:	362/736 - (49%)	Gaps:	59/736 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDSFWVQSAIGAIKAIAFVYDIITLPVYLVLQKPWKRRQDSRRVKAKPINQKMLVDE--SKYAPD 63
            |||....|:..|.:.|..::.      :||...     :.|..:::.|...:..:|.  |...|:
plant     1 MDSSSSSSSAAARRRINAIHS------HLVTSS-----RSSPLLRSNPTAGEFCLDNGYSVVLPE 54

  Fly    64 DIEAKIVRNDDNELTYRTTDPPRDVHVKMLQE-----NIDTLEKVFNYVAKTYTSKRCLGTRQIL 123
            .:      |..:...||:...|    .|::..     :|.||...|.:....:...:.||||
plant    55 KL------NTGSWNVYRSAKSP----FKLVSRFPDHPDIATLHDNFEHAVHDFRDYKYLGTR--- 106

  Fly   124 SEEDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELGQKPRENIVIFAETRAEWMIAA 188
                 |:.:|.|      |||||.|:.||.......|.||...|.....::.|:...|.||:|..
plant   107 -----VRVDGTV------GDYKWMTYGEAGTARTALGSGLVHHGIPMGSSVGIYFINRPEWLIVD 160

  Fly   189 HGCFKQAMPIVTVYATLGDDGVAHCITETEVTTVITSHDLLPKFKTLLDKCPLVKTIIYIEDQLQ 253
            |.|...:...|.:|.|||.|.|...:....|..:....:.|....:.|.:.|.|:.::.:...::
plant   161 HACSSYSYVSVPLYDTLGPDAVKFIVNHATVQAIFCVAETLNSLLSCLSEMPSVRLVVVVGGLIE 225

  Fly   254 KTETTGFKEGVKILPFNQVVKTGQDSKFEHVPPKGDDIAIIMYTSGSTGTPKGVLLSHKNCIATM 318
            ...:.....|||::.::.::..|:.:.....|||.||:|.|.||||:|||||||:|:|.|.||.:
plant   226 SLPSLPSSSGVKVVSYSVLLNQGRSNPQRFFPPKPDDVATICYTSGTTGTPKGVVLTHANLIANV 290

  Fly   319 KGFVDMVPIYPDDVLIGFLPLAHVFELVAESVCLMTGVPIGY--STPLTLIDTSSKIKRGCKGDA 381
            .|....|..:..||.|.:|||||::|...:.:.:..||.:|:  ...:.|:|           |.
plant   291 AGSSFSVKFFSSDVYISYLPLAHIYERANQILTVYFGVAVGFYQGDNMKLLD-----------DL 344

  Fly   382 TVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYK-TPLIDKLVFKK 445
            ..|:||..:|||.:.:||..||.:.|.:....|:.||...|..|.:.:..|.. :|:.|:|||.|
plant   345 AALRPTVFSSVPRLYNRIYAGIINAVKTSGGLKERLFNAAYNAKKQALLNGKSASPIWDRLVFNK 409

  Fly   446 VAKLMGGKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPL 510
            :...:||:||.:.||.:|||.:..|.:|.|....:.:|||:|||:...:.||..|...|..|.|.
plant   410 IKDRLGGRVRFMTSGASPLSPEVMEFLKVCFGGRVTEGYGMTETSCVISGMDEGDNLTGHVGSPN 474

  Fly   511 TVCDIRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKTNEDFFEEDGQRWFKTGDIGE 575
            ..|:::||:..|.||...::|:|:||:.:.|..:..||||...:|.| ..:|||  |..|||||.
plant   475 PACEVKLVDVPEMNYTSADQPHPRGEICVRGPIIFTGYYKDEIQTKE-VIDEDG--WLHTGDIGL 536

  Fly   576 IQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHL 640
            ....|.||||||||::.||..|||::..|:|:....|..:....:|||......||:|..:.:.|
plant   537 WLPGGRLKIIDRKKNIFKLAQGEYIAPEKIENVYAKCKFVGQCFIYGDSFNSSLVAVVSVDPDVL 601

  Fly   641 EELAQKHGLGDKSFEELCSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTA 705
            :..|...|:......|||::|.::.|:|.::....|:.:|:.:|...|:||..|.::.:.||:|.
plant   602 KSWAASEGIKGGDLRELCNNPRVKAAVLSDMDTVGREAQLRGFEFAKAVTLVLEPFTLENGLLTP 666

  Fly   706 AFKLKRKDIQDRYQHDINRMY 726
            .||:||...::.:...|..||
plant   667 TFKIKRPQAKEYFAEAITNMY 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acsl	NP_001260810.1	PLN02387	95..727	CDD:215217	208/640 (33%)
Acsl	NP_001260810.1	LC-FACS_euk	142..726	CDD:213293	195/586 (33%)
LACS6	NP_566265.1	PLN02736	41..691	CDD:178337	216/685 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53493
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820