Protein Alignment Acsl and Acsbg3

DIOPT Version :10

• Sequence 1: NP_001260810.1
• Gene: Acsl / 46068
• FlyBaseID: FBgn0263120
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_084417.1
• Gene: Acsbg3 / 78625
• MGIID: 1925875
• Length: 705
• Species: Mus musculus
• Alignment Length: 782
• Identity: 155/782 - (19%)
• Similarity: 294/782 - (37%)
• Gaps: 186/782 - (23%)

  Fly    39 QDSRRV-KAKPINQKMLVDESKYAPDDIEAKIVRNDDNEL-----TYRTTDPPRDVHVKMLQENI 97
            |.|||: |.|.|.:..:        ....:|..:.|:.|:     :|.|:.....|.::|.::.:
Mouse    11 QTSRRILKTKTILKNKI--------HSAISKKAQADNFEILTPGSSYWTSKREGQVQLRMGKDPL 67

  Fly    98 D-----TLEKVFNYVAKTYTSKRCLGTRQILSEEDEVQQNGRVFKKYNLGDYKWKTFT-----EA 152
            |     |:..:....|..|:....:|::               :||      .|:..|     ||
Mouse    68 DNEPPVTVPDLIMSAATKYSHYLAIGSK---------------YKK------SWQLLTYIEYYEA 111

  Fly   153 ERTAANFGRGLRELGQKPRENIVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVAHCITET 217
            .|.||   :...::|.:....:.|.....:||:||:.|........|.:.:::... ....|.||
Mouse   112 CRRAA---KAFLKVGLERFHGVGIMGINSSEWVIASIGAIMAGGISVGILSSISPK-ACQVIAET 172

  Fly   218 -EVTTVITSHD-LLPKFKTLLDKCPLVKTIIYIEDQLQKTETT-----GF---KEGVKILPFNQV 272
             |:...:..:| .|.|...:......:|.||...:.:|:.:..     ||   .:|:.....:::
Mouse   173 SEMDIFVVDNDRQLQKINQIQGYLKHLKAIIQYREDIQEAQPNLYSWKGFLDLADGISDEKLDKI 237

  Fly   273 VKTGQDSKFEHVPPKGDDIAIIMYTSGSTGTPKGVLLSHKNCIATMKGFVDMV----PIYPDDVL 333
            :.|          .|.:....::|..|:||..|.::|||.|...|....|..:    |....::|
Mouse   238 IDT----------LKPNQCCALVYNQGTTGPSKAIMLSHDNITWTTAAIVQSLGFKCPPQGQEIL 292

  Fly   334 IGFLPLA----HVFEL-VAESVC-----------LMTGVPIGYSTPLT--LIDTSSKIKRGCKGD 380
            :.:|||.    .:.:: ||.||.           ..:|:|   .||.|  |::...::
Mouse   293 VSYLPLCFPGIQILDVWVAISVAGTVYFPSLDSGKWSGLP---RTPGTGFLMELLREV------- 347

  Fly   381 ATVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQR-GYKT--------- 435
                :||....:|.:.||:...:..|....:||::.:        ..|..| |..|
Mouse   348 ----QPTTFCGIPWVWDRMLDSLKTKFLDSTAFRRRI--------DHWAMRMGLHTNKKLMMGEI 400

  Fly   436 ------PLIDKLVFKKVAKLMG-GKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETTSGA 493
                  .|..:|.|::..|.:| ...:..::.|..|.:.|.:...: :.:.:::.|||:|.|...
Mouse   401 HQPLCFGLAKRLTFERARKFLGLNHCQQFLNMGMGLPSGTLDFFLS-VNIPIMELYGLSECTGLH 464

  Fly   494 TVMD---YRDMTYGRTGGPLTVCDIRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKT 555
            ||.:   ||.::.|: ..|.|...:...| ::|          .|.:.|.|..:..||.:....|
Mouse   465 TVSNLQAYRILSAGK-ALPKTHTKVEKEN-KDG----------IGNLCIWGRHIFMGYLRDKQST 517

  Fly   556 NEDFFEEDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKT--------- 611
            ..   :.|...|..|.|:|.:..|..|.::....||:||.:||.|:...:|..::|
Mouse   518 ER---KVDTHGWLHTNDLGFLDFDKFLYVMGNNNDLIKLSSGEMVNPYPIEERVRTRIPIVRYAM 579

  Fly   612 ---------CGIIENICVYGDPTKQYTVALVVPNQNHLEEL--------AQKHGLGDKSFEELCS 659
                     |.::...|.....|.:       ...|...|:        :|...|.|..::.
Mouse   580 LVGQDAPYLCALLTLKCQINPETGE-------ARSNLTSEVVACCRKLRSQSTWLSDVLYDR--- 634

  Fly   660 SPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDINR 724
            .|::.:.|.:.|.:...:......::...:.|..: :|.|.|.:....|:.|..:...||.:|.:
Mouse   635 DPLVTEFINQGIEDVNSEAPTMGAKIIKWVILDND-FSVDGGELGPMSKMNRSIVVKIYQEEIQK 698

  Fly   725 MY 726
            :|
Mouse   699 LY 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsl	NP_001260810.1	LC_FACS_euk1	142..714	CDD:341294	130/654 (20%)
Acsbg3	NP_084417.1	ACSBG_like	95..700	CDD:341256	135/688 (20%)