Protein Alignment Acsl and Slc27a2

DIOPT Version :10

• Sequence 1: NP_001260810.1
• Gene: Acsl / 46068
• FlyBaseID: FBgn0263120
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_113924.2
• Gene: Slc27a2 / 65192
• RGDID: 71103
• Length: 620
• Species: Rattus norvegicus
• Alignment Length: 627
• Identity: 124/627 - (19%)
• Similarity: 214/627 - (34%)
• Gaps: 184/627 - (29%)

  Fly   148 TFTEAERTAANFGRGLRE-LGQKPRENIVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVA 211
            |:.:.:|.:....|.|.: ||.:..:.:.:|......::....|..|...|:..:...:....:.
  Rat    80 TYAQVDRRSNQVARALHDHLGLRQGDCVALFMGNEPAYVWLWLGLLKLGCPMACLNYNIRAKSLL 144

  Fly   212 HCITETEVTTVITSHDLLPKFKTLLDKCPLVKTIIYIEDQLQKTETTGFKEGVKILPFNQVVKTG 276
            ||........::.|.:|....:.:|   |.:|                 |||:.:.   .|.:|.
  Rat   145 HCFQCCGAKVLLASPELHEAVEEVL---PTLK-----------------KEGMSVF---YVSRTS 186

  Fly   277 QDSKFEHVPPKGDDI------------------AIIMYTSGSTGTPKGVLLSHK-----NCIATM 318
            ..:..:.|..|.|.:                  |:.:||||:||.||...::|.     ..:|..
  Rat   187 NTNGVDTVLDKVDGVSADPIPESWRSEVTFTTPAVYIYTSGTTGLPKAATINHHRLWYGTSLALR 251

  Fly   319 KGFVDMVPIYPDDVLIGFLPLAHVFELVAESVCLMTG----VPIGYSTPLTLIDTSSKIKRGC-K 378
            .|      |...||:...:||.|       |..||.|    :.:|.:..|....::|:....| |
  Rat   252 SG------IKAHDVIYTTMPLYH-------SAALMIGLHGCIVVGATFALRSKFSASQFWDDCRK 303

  Fly   379 GDATVLKPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYKTPLIDKLVF 443
            .:|||::                           :...|.::|.....|...|.:
  Rat   304 YNATVIQ---------------------------YIGELLRYLCNTPQKPNDRDH---------- 331

  Fly   444 KKVAKLMGGKVRIIMSGGAPLSADT-HEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTG 507
                     ||:|.:..|  |..|. .|.||....:.:.:.|..||...|.       |.|.|..
  Rat   332 ---------KVKIALGNG--LRGDVWREFIKRFGDIHIYEFYASTEGNIGF-------MNYPRKI 378

  Fly   508 GPL---TVCDIRLVNWEEGNYRV-TNKP----------YPQGEVLIGGECVSQ--------GYYK 550
            |.:   .....::|..|...|.| .::|          .|:|||   |..:.:        ||
  Rat   379 GAVGRENYLQKKVVRHELIKYDVEKDEPVRDANGYCIKVPKGEV---GLLICKITELTPFFGY-- 438

  Fly   551 LPGKTN------EDFFEEDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESEL 609
            ..|||.      .|.|:: |..:|.:||:..|..:..:...||..|..:.: ||.|:..:|...:
  Rat   439 AGGKTQTEKKKLRDVFKK-GDVYFNSGDLLMIDRENFIYFHDRVGDTFRWK-GENVATTEVADIV 501

  Fly   610 KTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQKHGLGDKSFEELCSSPIIEKAILKEIAEH 674
            .....:|.:.|||.|         ||...      .:.|:.....:|  :.....|.:.:.|:|:
  Rat   502 GLVDFVEEVNVYGVP---------VPGHE------GRIGMASIKMKE--NYEFNGKKLFQHISEY 549

  Fly   675 ARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQD 716
                 |..|..|..:.:      .|...:|..||.::..:.:
  Rat   550 -----LPSYSRPRFLRI------QDTIEITGTFKHRKVTLME 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsl	NP_001260810.1	LC_FACS_euk1	142..714	CDD:341294	124/623 (20%)
Slc27a2	NP_113924.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	124/627 (20%)