Protein Alignment Acsl and ACSL1

DIOPT Version :9

• Sequence 1: NP_001260810.1
• Gene: Acsl / 46068
• FlyBaseID: FBgn0263120
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_001273637.1
• Gene: ACSL1 / 2180
• HGNCID: 3569
• Length: 698
• Species: Homo sapiens
• Alignment Length: 649
• Identity: 213/649 - (32%)
• Similarity: 340/649 - (52%)
• Gaps: 55/649 - (8%)

  Fly    95 ENIDTLEKVFNYVAKTYTSKRCLGTRQILSEEDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANF 159
            :::.||.:.|....:...:..|||:|    :.|:              .|:|.::.:....:...
Human    87 DDVTTLYEGFQRGIQVSNNGPCLGSR----KPDQ--------------PYEWLSYKQVAELSECI 133

  Fly   160 GRGLRELGQK--PRENIVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVAHCITETEVTTV 222
            |..|.:.|.|  |.:.|.|||:.|.||:|...|||..:|.||.:|.|||::.:.:.:.:.|::.|
Human   134 GSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLV 198

  Fly   223 ITSHDLLPKFKTLLD-----KCPLVKTIIYIEDQLQKTETTGFKEGVKILPFNQVVKTGQDSKFE 282
            ..  |...|.|.||:     ..|.:|.|:.::....:....|.:.||::.....:...|:.::.:
Human   199 FV--DKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRK 261

  Fly   283 HVPPKGDDIAIIMYTSGSTGTPKGVLLSHKN----CIATMKGFVDMVPIYPDDVLIGFLPLAHVF 343
            ..||..:|:|:|.:|||:||.|||.:::|:|    |.|.:|...:.|...|||.||.||||||:|
Human   262 PKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMF 326

  Fly   344 ELVAESVCLMTGVPIGY--STPLTLIDTSSKIKRGCKGDATVLKPTCMTSVPLILDRISKGINDK 406
            |.|.|.|.|..|..||:  .....|:|           |..||:||....||.:|:|:...|..:
Human   327 ERVVECVMLCHGAKIGFFQGDIRLLMD-----------DLKVLQPTVFPVVPRLLNRMFDRIFGQ 380

  Fly   407 VNSGSAFKKSLFKFLYQYKVKWVQRGY--KTPLIDKLVFKKVAKLMGGKVRIIMSGGAPLSADTH 469
            .|  :..|:.|..|..:.|...::.|.  ...|.|:|:|.||...:||:||::::|.||:||...
Human   381 AN--TTLKRWLLDFASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVL 443

  Fly   470 EQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPLTVCDIRLVNWEEGNYRVTNKPYPQ 534
            ..::..|..:..:|||.||.|:|..:....|.|.|..|.|:....|:||:.||.||....   .:
Human   444 TFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAE---GE 505

  Fly   535 GEVLIGGECVSQGYYKLPGKTNEDFFEEDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEY 599
            |||.:.|..|.|||.|.|.||.| ..::||  |..|||||:...:|.||||||||.:.||..|||
Human   506 GEVCVKGPNVFQGYLKDPAKTAE-ALDKDG--WLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEY 567

  Fly   600 VSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQKHGLGDKSFEELCSSPIIE 664
            ::..|:|:.......:..:.|:|:..:.:.:|:|||:...|...|||.|. :.||||||.:..::
Human   568 IAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGF-EGSFEELCRNKDVK 631

  Fly   665 KAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDINRMYAS 728
            ||||:::....:...|:.:|....|||..|::|.|.||:|...|.||.::::.::..|:.:|::
Human   632 KAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELRNYFRSQIDDLYST 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsl	NP_001260810.1	PLN02387	95..727	CDD:215217	212/646 (33%)
		LC-FACS_euk	142..726	CDD:213293	204/598 (34%)
ACSL1	NP_001273637.1	LC-FACS_euk	116..694	CDD:341250	204/613 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53493
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820