Protein Alignment Acsl and acs-15

DIOPT Version :10

• Sequence 1: NP_001260810.1
• Gene: Acsl / 46068
• FlyBaseID: FBgn0263120
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_493856.3
• Gene: acs-15 / 187666
• WormBaseID: WBGene00019920
• Length: 703
• Species: Caenorhabditis elegans
• Alignment Length: 654
• Identity: 185/654 - (28%)
• Similarity: 318/654 - (48%)
• Gaps: 81/654 - (12%)

  Fly   107 VAKTYTSKR---CLGTRQILSEEDEVQQNGRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELGQ 168
            :..||...|   .:|.:::|.:  .|.:||::       :::|.|:.:|...:.|..:.:|:||.
 Worm    77 ILTTYAGIRRGPTVGGKEMLGK--RVMKNGKL-------EWEWITYEQAFEISDNVSQAIRKLGI 132

  Fly   169 K--PRENIVIFAETRAEWMI---AAHGCFKQAMPIVTVYATLGDDGVAHCITETEVTTV-ITSHD 227
            :  .:.||.|:::.|.||::   |.|.....::||   |..:.::.:.:.....|:..: :.|.|
 Worm   133 EIGDKSNIGIYSKNRPEWVLSDMAIHNFSNVSVPI---YDNIPNEDMHYITNLCEIPLMFVDSED 194

  Fly   228 LLPKFKT---LLDKCPLVKTIIYI------EDQLQ-KTETTGFKEGVKILPFNQVVKTGQDSKFE 282
                 ||   :.||..|.|::.||      .|::: ..|:..|    ::..|::.|:.|:..:..
 Worm   195 -----KTTQLIKDKTYLSKSLKYIVQFDKVSDEMKAMAESNNF----QLWSFDEFVELGKKHEHR 250

  Fly   283 -HVPPKGDDIAIIMYTSGSTGTPKGVLLSHKNCIATMKGFVDMVPIYPD-DVLIGFLPLAHVFEL 345
             |.||..:.:|.|.:|||:||.|||.:|:|.|..:|.....:...:..: |..:.:||||||:|.
 Worm   251 PHAPPTPETLATISFTSGTTGRPKGAMLTHLNLCSTTVACEEFEHVEGELDSYLSYLPLAHVYER 315

  Fly   346 VAESVCLMTGVPIGYS--TPLTLIDTSSKIKRGCKGDATVLKPTCMTSVPLILDRISKGINDKV- 407
            .........|..||:|  .|..|::           |...|.|.....||.:|.:|.|.:..:|
 Worm   316 HCTLAHFKIGSRIGFSRGDPALLVE-----------DIQALAPRTFACVPRVLGKIYKSVMSQVQ 369

  Fly   408 ---------NSGSAFKKSLFKFLYQYKVKWVQRGYKTPLIDKLVFKKVAKLMGGKVRIIMSGGAP 463
                     ||..|:|      ||.||:  ..:..:..|:||.:..|:..::|..::..:...|.
 Worm   370 DKPVKKMILNSAIAYK------LYHYKM--TGKATRDTLVDKYILHKIQMILGPNIKQFLIPAAK 426

  Fly   464 LSADTHEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPLTVCDIRLVNWEEGNYRVT 528
            ....:....:....:|:::.||||||:...|:....|| .|..|.|::...|:||:..|..|.|.
 Worm   427 TDNSSMRFARGAFGIEILELYGLTETSGPTTIQLVGDM-LGSVGPPISCTSIKLVDIAELGYFVD 490

  Fly   529 NKPYPQGEVLIGGECVSQGYYKLPGKTNEDFFEEDGQRWFKTGDIGEIQADGVLKIIDRKKDLVK 593
            ..   .||||:.|..|:.||||.| |.....|.|||  :.||||||:...:|.|::|||:.:::|
 Worm   491 EN---GGEVLVKGHNVTSGYYKDP-KATASAFTEDG--FMKTGDIGKFTPEGTLQLIDRRDNVLK 549

  Fly   594 LQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQ-KHGLGDKSFEEL 657
            |..||:|:....||...:...::.|||:|:..|.:.||:|||:..:|...|. :|.:..|::|||
 Worm   550 LPQGEFVAPDLTESLYISSKFVQQICVHGNKEKPWLVAVVVPDPEYLASHANLEHNIEGKTYEEL 614

  Fly   658 CSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDRYQHDI 722
            |..|.:.:.:|::..:..::....::|...||.|....:||..||.|...|.||..|...::..|
 Worm   615 CKIPALAEDVLRDFVDLTKEHNRPRHEGVFAIHLTPIAFSPQNGLTTPTHKNKRTAIAQFFKKQI 679

  Fly   723 NRMY 726
            ..|:
 Worm   680 VEMF 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsl	NP_001260810.1	LC_FACS_euk1	142..714	CDD:341294	174/602 (29%)
acs-15	NP_493856.3	Adenylate forming domain, Class I superfamily	107..683	CDD:473059	176/613 (29%)