Protein Alignment Acsl and acs-4

DIOPT Version :10

• Sequence 1: NP_001260810.1
• Gene: Acsl / 46068
• FlyBaseID: FBgn0263120
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_498568.1
• Gene: acs-4 / 176005
• WormBaseID: WBGene00018152
• Length: 731
• Species: Caenorhabditis elegans
• Alignment Length: 732
• Identity: 320/732 - (43%)
• Similarity: 446/732 - (60%)
• Gaps: 43/732 - (5%)

  Fly     5 WVQSAIGAIKAIAFVYDIITLPVYLVLQKPWKRRQDSRRVKAKPINQKMLVDESKYAPDDIEAKI 69
            |::.|:..::...|:||.:....|.:...|.::.:.|.||||..:
 Worm    27 WIRVAMAILRVWFFIYDCLNYLPYQLFNSPTEKLRKSERVKANWV-------------------- 71

  Fly    70 VRNDDNELTYRTTDPPRDV--HVKMLQENIDTLEKVFNYVAKTYTSKRCLGTRQILSEEDEVQQN 132
               ||.:      .|.|::  |........||::||:....:.|....||||||::...::.|..
 Worm    72 ---DDRD------GPIRNIQGHASETFPGKDTVDKVWRKCVELYDESPCLGTRQLIEVHEDKQPG 127

  Fly   133 GRVFKKYNLGDYKWKTFTEAERTAANFGRGLRELG---QKPRENIVIFAETRAEWMIAAHGCFKQ 194
            ||||:|::||:|.|:::.|.|...|....|:::|.   |.|:  :||||||||:|:|.|..||:.
 Worm   128 GRVFEKWHLGEYVWQSYKEVETQVARLAAGIKDLAHEEQNPK--VVIFAETRADWLITALACFRA 190

  Fly   195 AMPIVTVYATLGDDGVAHCITETEVTTVITSHDLLPKFKTLLDKCPLVKTIIY---IEDQLQKTE 256
            .:.|||||||||:|.:||.|.|||.|.::||.:||||..||..|||.:||:||   ::.:....|
 Worm   191 NVTIVTVYATLGEDAIAHAIGETEATILVTSSELLPKIVTLGKKCPTLKTLIYFAPVDQKAPAPE 255

  Fly   257 TTGFKEGVK-ILPFNQVVKTGQDSKFEHVPPKGDDIAIIMYTSGSTGTPKGVLLSHKNCIATMKG 320
            ...|::..| :|..:.::...|:...|....| .|||:||||||:||.||||:|.|:|.:|.:.|
 Worm   256 LAPFRDQFKHVLSLSGLLTRNQEQVKESTAVK-SDIALIMYTSGTTGQPKGVILLHQNVVAALLG 319

  Fly   321 FVDMVPIYPD-DVLIGFLPLAHVFELVAESVCLMTGVPIGYSTPLTLIDTSSKIKRGCKGDATVL 384
            ..|.|.|..: |..||:|||||:.||.||..||..|..:|||:||||.|.:|||::|..||...|
 Worm   320 QGDGVGIICNADTYIGYLPLAHILELDAELTCLTKGAKVGYSSPLTLHDRASKIQKGTHGDCHAL 384

  Fly   385 KPTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYKTPLIDKLVFKKVAKL 449
            :||.|.:||.|:|||.|.::::|.:...|.:.|||..|:.|......||.:|.:|::||||:.:|
 Worm   385 RPTLMAAVPAIMDRIFKAVSEEVAASPRFMQELFKLNYERKRSRYLEGYCSPFLDRIVFKKIRRL 449

  Fly   450 MGGKVRIIMSGGAPLSADTHEQIKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPLTVCD 514
            :|||:|.::||||||:|:|...:..|:|..::||||||||...|.|.|..|::.|..|.|:...|
 Worm   450 LGGKLRGVLSGGAPLNAETQRFMNICMCCPVVQGYGLTETCGAACVADINDLSTGTVGPPVRCSD 514

  Fly   515 IRLVNWEEGNYRVTNKPYPQGEVLIGGECVSQGYYKLPGKTNEDFFEEDGQRWFKTGDIGEIQAD 579
            |.|..|.||.|...|.| ||||:||.||.:|.||||.|.||.|||....|:.:|.|||||:.:.|
 Worm   515 IALREWSEGGYSPFNDP-PQGEILISGENISPGYYKQPEKTAEDFITYKGKVYFATGDIGQKRDD 578

  Fly   580 GVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELA 644
            |.|.||||||||||||.||||||.|||..|..|.|::||||||...:...||||||||.|||::|
 Worm   579 GSLLIIDRKKDLVKLQHGEYVSLAKVECALLNCPIVDNICVYGSGMEDSVVALVVPNQKHLEKIA 643

  Fly   645 QKHGLGDKSFEELCSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKL 709
            :..|:.....:.:|....:..|..|::.|||:|.||.:.|:||||.||.|:|:||.||:|.|.||
 Worm   644 EAEGVSTSEMKTMCEDKKVIAAYKKQLEEHAKKSKLSRSEIPAAIHLCPEIWTPDTGLLTEALKL 708

  Fly   710 KRKDIQDRYQHDINRMY 726
            |||.||..||..::.:|
 Worm   709 KRKPIQMAYQKTLDDLY 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsl	NP_001260810.1	LC_FACS_euk1	142..714	CDD:341294	280/579 (48%)
acs-4	NP_498568.1	LC_FACS_euk1	137..713	CDD:341294	280/579 (48%)