Protein Alignment Acsl and SLC27A5

DIOPT Version :10

• Sequence 1: NP_001260810.1
• Gene: Acsl / 46068
• FlyBaseID: FBgn0263120
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_036386.1
• Gene: SLC27A5 / 10998
• HGNCID: 10999
• Length: 690
• Species: Homo sapiens
• Alignment Length: 649
• Identity: 132/649 - (20%)
• Similarity: 215/649 - (33%)
• Gaps: 203/649 - (31%)

  Fly   148 TFTEA--ERTAANFGRGLRELGQKPRENIVIFAE-----TRAEWMIAAH---------------- 189
            ||.:|  .|..|..||.|. :...|....|.|.|     .:|.|.:.|.
Human   115 TFVDAFERRARAQPGRALL-VWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALL 178

  Fly   190 GCFKQAMPIVTVYATLGDDG--------------VAHCITETEVTTVITSHDLLPKFKTLLDKCP 240
            ....||:|.:.::..|...|              :||.:..:....::...||....:.:|.|..
Human   179 VLASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQ 243

  Fly   241 LVKTIIYIEDQLQKTETTGFKEGVKILPFNQVVKTGQDSKFEHVPPKGDDI---------AIIMY 296
            ......:.......|...|            .:....|:...|..|.  |:         |:.:|
Human   244 AENIRCFYLSHTSPTPGVG------------ALGAALDAAPSHPVPA--DLRAGITWRSPALFIY 294

  Fly   297 TSGSTGTPKGVLLSHKNCIATMKGFVDMVPIYPDDVLIGFLPLAHVFELVAESVCLMTGVPIGYS 361
            |||:||.||..:|:|:. :..|...:.:.....|||:...|||.||..||       .|:
Human   295 TSGTTGLPKPAILTHER-VLQMSKMLSLSGATADDVVYTVLPLYHVMGLV-------VGI----- 346

  Fly   362 TPLTLIDTSSKIKRGC--KGDATVLKPTCMTS----------VPLILDRISKGINDKVNSGSAFK 414
                         .||  .|...||.|...||          |.:||                :.
Human   347 -------------LGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVIL----------------YV 382

  Fly   415 KSLFKFLYQYKVKWVQRGYKTPLIDKLVFKKVAKLMGGKVRIIMSGGAPLSADTHEQIKTCL-CL 478
            ..|.::|.....:...|.:                   .||:.|..|  |.||..|..:... .:
Human   383 GELLRYLCNIPQQPEDRTH-------------------TVRLAMGNG--LRADVWETFQQRFGPI 426

  Fly   479 ELIQGYGLTETTSGATVMDYRDMTYGRTG--GPLTVCDIRLVN-WEEGNYRV-TNKPYPQGEVLI 539
            .:.:.||.||...|  :::|    .||.|  |.:: |.:|::: :|...:.: ..:|....:
Human   427 RIWEVYGSTEGNMG--LVNY----VGRCGALGKMS-CLLRMLSPFELVQFDMEAAEPVRDNQ--- 481

  Fly   540 GGECVSQGY------------------YKLPGKTNEDFF----EEDGQRWFKTGDIGEIQADGVL 582
             |.|:..|.                  |:.|.:.:|...    .:.|..::.|||:..:..:|.|
Human   482 -GFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFL 545

  Fly   583 KIIDRKKDLVKLQAGEYVSLGKVESELKTCGIIENICVYGDPTKQYTVALVVPNQNHLEELAQKH 647
            ...||..|..:.: ||.||..:||..|.....::.:.|||         :.||.......:|...
Human   546 YFRDRLGDTFRWK-GENVSTHEVEGVLSQVDFLQQVNVYG---------VCVPGCEGKVGMAAVQ 600

  Fly   648 GLGDKSFEELCSSPIIEKAILKEIAEHARKCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKR 711
            ....::|:.            :::.:|.| ..|..|..|..|.:      .|...||:.|||.:
Human   601 LAPGQTFDG------------EKLYQHVR-AWLPAYATPHFIRI------QDAMEVTSTFKLMK 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsl	NP_001260810.1	LC_FACS_euk1	142..714	CDD:341294	132/649 (20%)
SLC27A5	NP_036386.1	hsFATP2a_ACSVL_like	138..680	CDD:341261	124/625 (20%)