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Protein Alignment MYBPC2 and MnM

DIOPT Version :10

Sequence 1:	NP_004524.3	Gene:	MYBPC2 / 4606	HGNCID:	7550	Length:	1141	Species:	Homo sapiens
Sequence 2:	NP_647779.2	Gene:	MnM / 38384	FlyBaseID:	FBgn0035410	Length:	1443	Species:	Drosophila melanogaster

Alignment Length:	534	Identity:	139/534 - (26%)
Similarity:	220/534 - (41%)	Gaps:	90/534 - (16%)

- Green bases have known domain annotations that are detailed below.

Human   621 TNPV-GEDVASIFLQVVDVPDPPEAVRITSVG-----EDWAILVWEPPMYDGGKPVTGYLVERKK 679
            |:|. |....::..:..:.|.||....:|.|.     .|...|.|:.|::|||.|:|||.||.::
  Fly    10 THPQGGRPKKNVHWKSAERPSPPGRPILTPVALPEQQPDVVNLRWDRPLHDGGSPITGYTVEHRR 74

Human   680 KGSQRWMKLNFEVFTETTYESTKM-IEGI----LYEMRVFAVNAIGVSQPSMNTKPF-MPIAPTS 738
            .||..|::.     |.|..:...: |.|:    .|:.|.||.|.:|.|..|..:.|. :.:...:
  Fly    75 MGSPHWVRA-----TPTPVDRCDVCISGLEPGWRYQFRCFAENIVGRSDASELSDPLTVTLQRNA 134

Human   739 EPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV---ERCGFTVKN 800
            ..:...::::.||......|...|:...|.....:.:..:|.|.:....|:.|   |.....:..
  Fly   135 ITVPRFIDELVDTNAVEDERIEFRVRILGEPPPEINWFKDGYEIFSSRRTKIVNDNEASVLVIHQ 199

Human   801 LPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ 865
            :........:....|.||  ...|.|:.:    :..||||||||......|.:..|.|.|.|...
  Fly   200 VALTDEGEIKCTATNRAG--HVITKARLM----VQAPPKIRLPRTYEDGLIVEADEVLRLKVGVA 258

Human   866 GKPRPQVVWTKGG---APLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRI 927
            |:|.|.:.|...|   ||  ..|..|..::.:::..:....|.|.|||.:.......:|:.:..:
  Fly   259 GQPPPAITWLHEGEVIAP--GGRFEVSNTEKNSLLKIDNVLREDRGEYMVKAWNRLGEDSTSFLV 321

Human   928 RVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWF----NVYER--- 985
            .|..:..||....:...:|.:|.:.|.||.|||..:|..|.|        |:|    ||:.:
  Fly   322 TVTARPNPPGTPKLNMSFGKSATLSWTAPLDDGGCKIGNYIV--------EYFRVGWNVWLKAAT 378

Human   986 NRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARIL-----KTGITFKP-----FEYK 1040
            .|..|.|:.|||.|:||.|||..||..|||:..|.|:    :|     |.||| ||     ....
  Fly   379 TRALSTTLHDLIEGSEYKFRVKAENPYGLSEPSGESE----LLFIPDPKRGIT-KPKSATRIAGD 438

Human  1041 EHD--------FRMAPKFLT-----PLIDRVVVAGYSAALNCAVRGHPKPKVVWMKN-------- 1084
            |.|        .::.|:..|     |..|  ...|.|...:.:.:..|||:::..:.
  Fly   439 EKDKPKTGAGGMQVPPRRKTLSPPRPQAD--ASTGMSPKQSPSAKRKPKPQLIDNEQLTHEMSYG 501

Human  1085 ------KMEIREDP 1092
                  ||::|:.|
  Fly   502 TSDHALKMDVRKSP 515

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.