Protein Alignment Sply and GAD1

DIOPT Version :9

• Sequence 1: NP_652032.1
• Gene: Sply / 46059
• FlyBaseID: FBgn0010591
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_013976.1
• Gene: GAD1 / 855291
• SGDID: S000004862
• Length: 585
• Species: Saccharomyces cerevisiae
• Alignment Length: 408
• Identity: 92/408 - (22%)
• Similarity: 166/408 - (40%)
• Gaps: 83/408 - (20%)

  Fly    53 LYIRGKRQFFKFAKKIPAVRRQVETELAKAK---NDFETEIKKS------NAHLTYSE------T 102
            |:..|.:|     |....:..:|..:||..:   ||.:....:|      |...|.|:      :
Yeast     2 LHRHGSKQ-----KNFENIAGKVVHDLAGLQLLSNDVQKSAVQSGHQGSNNMRDTSSQGMANKYS 61

  Fly   103 LPEKGLSKEEILRLVDEHLK---TGHYNWRDGRVSGAVYGYKPDLV-ELVTEVYGKASYTNPLHA 163
            :|:|||..:...:|:...|.   ..|.|     ::..|..:..|.. :|:.|...|    |....
Yeast    62 VPKKGLPADLSYQLIHNELTLDGNPHLN-----LASFVNTFTTDQARKLIDENLTK----NLADN 117

  Fly   164 DLFPGVCKMEAEVVRMACNLFHGN--SASCGTMTTGGTESIV---MAMKAYRDFAREYKG--ITR 221
            |.:|.:.::....:.|...|:|.|  ....|..|||.:|:|:   :|||...:...:..|  .::
Yeast   118 DEYPQLIELTQRCISMLAQLWHANPDEEPIGCATTGSSEAIMLGGLAMKKRWEHRMKNAGKDASK 182

  Fly   222 PNIVVPKTVHAAFDKGGQYFNIHVRSVDVDPETYE-VDIKKFKRAINRNTI---LLVGSAPNFPY 282
            |||::......|.:|..:||.:..|.|.|...::. :|.:.....::.|||   :::|:...
Yeast   183 PNIIMSSACQVALEKFTRYFEVECRLVPVSHRSHHMLDPESLWDYVDENTIGCFVILGTTYT--- 244

  Fly   283 GTIDDIEAIA----ALGVKY------DIPVHVDACLGSFVVALVRNAGYKLRPFDFEVK------ 331
            |.::::|.:|    .:..|:      |||:|.|...|.|::           ||.||.:
Yeast   245 GHLENVEKVADVLSQIEAKHPDWSNTDIPIHADGASGGFII-----------PFGFEKEHMKAYG 298

  Fly   332 ---------GVTSISADTHKYGFAPKGSSVILYSDKKYKDHQFTVTTDWPGGVYGSPTVNGSRAG 387
                     .|.|::...||:|....|...:|:.|:.....:......:.|||..:..:|.||.|
Yeast   299 MERWGFNHPRVVSMNTSGHKFGLTTPGLGWVLWRDESLLADELRFKLKYLGGVEETFGLNFSRPG 363

  Fly   388 GIIAACWATMMSFGYDGY 405
            ..:...:...:|.|:.||
Yeast   364 FQVVHQYFNFVSLGHSGY 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sply	NP_652032.1	DOPA_deC_like	132..494	CDD:99743	71/311 (23%)
GAD1	NP_013976.1	Glu-decarb-GAD	41..522	CDD:130848	82/364 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.875	Normalized mean entropy	S949
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760