Protein Alignment Sply and Tdc1

DIOPT Version :10

• Sequence 1: NP_652032.1
• Gene: Sply / 46059
• FlyBaseID: FBgn0010591
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_610226.2
• Gene: Tdc1 / 35573
• FlyBaseID: FBgn0259977
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 486
• Identity: 86/486 - (17%)
• Similarity: 167/486 - (34%)
• Gaps: 120/486 - (24%)

  Fly   111 EEILRLVDEHLKTGHYNWRDGRVSGAVYGYKPD-------LVELVTEVYGKASYTNPLHADLFPG 168
            :::|...::.:..|..:|...:    .:.|.|.       |.::::...|...::        ..
  Fly    54 KDVLEDFEQKIMPGVVHWNHPK----FFAYFPSGNSFPSVLGDMLSSAIGSIGFS--------WA 106

  Fly   169 VCKMEAEVVRMACNLF-------------HGNSASCGTMTTGGTESIVMAMKAYRDFA-REYKGI 219
            .|...||:..:..|.:             ...|...|.:....:|.:::::...|..| .|.||.
  Fly   107 SCPAAAELETIVMNWYAKALGLPKAFVSDAPGSTGGGALQGSASECVLVSLITARARAISELKGQ 171

  Fly   220 TR-------PNIV--VPKTVHAAFDKGGQYFNIHVRSVDVDPETYEVDIKKFKRAINRNTILLVG 275
            |.       |:::  ..:..|::.:|..:...:.:|.:|.| |...:.:...::||..:  :..|
  Fly   172 TSVHDSVFLPSLIAYASREAHSSVEKATKMALVKLRIIDAD-EHGRMRVDLLRQAIQND--VNAG 233

  Fly   276 SAPNFPYGTI--------DDIEAIAALGVKY-DIPVHVDACL--GSFVVALVRNAGYKLRPFDFE 329
            ..|.|...|:        |||..|..:..:. .|.:|||...  .||::.       ::|.|...
  Fly   234 LTPFFVVATVGTTGGCAFDDITEIGKVCRQVSSIWLHVDGAYAGNSFILP-------EMRVFSAG 291

  Fly   330 VKGVTSISADTHKYGFAPKGSSVILYSD-----------KKYKDHQFTVTTDWPGGVYGSPTVNG 383
            ::...|.:.:.:|.......:|.:...|           ..|..|:.....|:..  ||.|....
  Fly   292 LEYADSFNTNPNKLLLTNFDASALWVRDVMNLKSALNVNPLYLRHEHLTGVDYRH--YGIPLSRR 354

  Fly   384 SRAGGIIAACWATMMSFGYDGYLEATKRIVDTARYIERGVRDIDGIFIFGKPATSVIALGSNVFD 448
            .||    ...|....::|..|..|..:..:..|:..|..||..:...:     .:.:.||...|.
  Fly   355 FRA----LKLWFVFRTYGIRGLQEYIRNHMALAKKFEMLVRKDERFEV-----RNDVHLGLVCFR 410

  Fly   449 IFRLSDS-----LCKLGWNLNALQFPSG------IHLCVTDMH-TQPGVADKFIADVRSCTAEIM 501
            : |..|.     |.::..:......|:.      |..|||..| |:..:.:.: ..::....||:
  Fly   411 M-RTGDEPNHMLLAQINHSGKMHMTPAKFNGRYVIRFCVTYEHATEKDILEAW-TQIKCFAEEIL 473

  Fly   502 KD---------------------PGQPVVGK 511
            :|                     |..||.||
  Fly   474 RDHQLESSSVPTTPEGSERTSSEPLAPVAGK 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sply	NP_652032.1	DOPA_deC_like	132..494	CDD:99743	75/425 (18%)
Tdc1	NP_610226.2	Pyridoxal_deC	35..412	CDD:395219	68/391 (17%)