Protein Alignment Sply and GADL1

DIOPT Version :9

• Sequence 1: NP_652032.1
• Gene: Sply / 46059
• FlyBaseID: FBgn0010591
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_997242.2
• Gene: GADL1 / 339896
• HGNCID: 27949
• Length: 521
• Species: Homo sapiens
• Alignment Length: 380
• Identity: 79/380 - (20%)
• Similarity: 135/380 - (35%)
• Gaps: 87/380 - (22%)

  Fly   104 PEKGLSKEEILR-LVDEHLKTGHYNWRDGRVSGAVYGYKPDLVELVTEVYGKASYTNPLHADLFP 167
            |.|.|   |:.| ::...:||.|..:.:...:|  ..|...:...:||....:.||    .::.|
Human    95 PHKLL---ELCRDVIHYSVKTNHPRFFNQLYAG--LDYYSLVARFMTEALNPSVYT----YEVSP 150

  Fly   168 GVCKMEAEVVRMACNLFHGNSASCGTMTTGGTESIVMAMKAYRDFAREYK-----------GITR 221
            ....:|..|::.... |.|.....|....||:.|.:.||...|     ||           |..|
Human   151 VFLLVEEAVLKKMIE-FIGWKEGDGIFNPGGSVSNMYAMNLAR-----YKYCPDIKEKGLSGSPR 209

  Fly   222 PNIVVPKTVHAAFDKGGQYFNI---HVRSVDVD------PETYEVDIKKFKR---------AINR 268
            ..:......|.:..|...:..|   :|..|:.|      ||..|..:.:.::         |.:.
Human   210 LILFTSAECHYSMKKAASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVCATSG 274

  Fly   269 NTILLVGSAPNFPYGTIDDIEAIAALGVKYDIPVHVDACLGSFVVALVRNAGYKLRPFDFEVKGV 333
            .|:|          |..|.::.||.:..::.:.:||||..|.  .||:.....||      :.|:
Human   275 TTVL----------GAFDPLDEIADICERHSLWLHVDASWGG--SALMSRKHRKL------LHGI 321

  Fly   334 ---TSISADTHKYGFAPKGSSVILYSDKK---------------YKDHQFTVTTDWPGGVYGSPT 380
               .|::.:.||...|......:|..||.               .:|..:.|:.|     .|..:
Human   322 HRADSVAWNPHKMLMAGIQCCALLVKDKSDLLKKCYSAKASYLFQQDKFYDVSYD-----TGDKS 381

  Fly   381 VNGSRAGGIIAACWATMMSFGYDGYLEATKRIVDTARYIERGVRDIDGIFIFGKP 435
            :..||..... ..|.|..:.|..|..|...|.:..:||:...::..:|..:..:|
Human   382 IQCSRRPDAF-KFWMTWKALGTLGLEERVNRALALSRYLVDEIKKREGFKLLMEP 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sply	NP_652032.1	DOPA_deC_like	132..494	CDD:99743	71/351 (20%)
GADL1	NP_997242.2	AAT_I	77..445	CDD:302748	79/380 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810