Protein Alignment Sply and Tdc2

DIOPT Version :10

• Sequence 1: NP_652032.1
• Gene: Sply / 46059
• FlyBaseID: FBgn0010591
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 94/513 - (18%)
• Similarity: 174/513 - (33%)
• Gaps: 159/513 - (30%)

  Fly    88 TEIKKSNAHL-----TYSETLPEKGLSK----------------------EEILRLVDEHLKTGH 125
            ||.:|....:     .|.|||.|:.::.                      ::|:|.|::.:..|.
  Fly     4 TEFRKRGMEMVEYICNYLETLNERRVTPSVEPGYLRHLLPPEAPQEPEDWDQIMRDVEDKIMPGV 68

  Fly   126 YNWRDGRVSGAVYGYKPD-------LVELVTEVYGKASYT---NPLHADLFPGVCKMEAEVVRMA 180
            .:|:..|    .:.|.|.       |.:::.:..|...::   :|...:|...|.....:.:.:.
  Fly    69 THWQHPR----FHAYFPAGNSFPSILGDMLGDGIGCIGFSWAASPACTELETIVLDWLGKAIGLP 129

  Fly   181 CN---LFHGNSASCGTMTTGGTESIVMAM-----------KAYRDFAREYKGITRPNIVVPKTVH 231
            .:   |..|::.. |.:.|..:|.:::.|           ||...|..|...:::......|..|
  Fly   130 DHFLALKEGSTGG-GVIQTSASECVLVTMLAARAQALKRLKAQHPFVEEGHLLSKLMAYCSKEAH 193

  Fly   232 AAFDKGGQYFNIHVRSVDVDPETYEVDIKKFKRAINRNTIL-------LVGSAPNFPYGTI---- 285
            :..:|......:.:|.::.|.:.          ::...||.       |.|..|.|...|:
  Fly   194 SCVEKAAMICFVKLRILEPDDDA----------SLRGQTIYEAMEEDELQGLVPFFVSTTLGTTG 248

  Fly   286 ----DDIEAIAALGVKY-DIPVHVDACL--GSFVVALVRNAGYKLRPFDFEVKGV---TSISADT 340
                |::..|.....:: .:.:||||..  .||:..       :|:|.   :||:   .|.:.:.
  Fly   249 SCAFDNLPEIGKQLQRFPGVWLHVDAAYAGNSFICP-------ELKPL---LKGIEYADSFNTNP 303

  Fly   341 HKYGFAPKGSSVI-----------LYSDKKYKDHQFT-VTTDWPGGVYGSPTVNGSRAGGIIAAC 393
            :|:.......|.:           |..|..|..|.:: ...|:..  :|.|.....|:    ...
  Fly   304 NKWLLTNFDCSTLWVRDRIRLTSALVVDPLYLKHGYSDAAIDYRH--WGVPLSRRFRS----LKL 362

  Fly   394 WATMMSFGYDGYLEATKRIVDTARYIERGVRDIDGIFIFGKPATSVIALGSNVFDI--------- 449
            |..:.|:|..|.....:..:..|:..|.                  :.|....|:|
  Fly   363 WFVLRSYGISGLQHYIRHHIKLAKRFEE------------------LVLKDKRFEICNQVKLGLV 409

  Fly   450 -FRLSDSLCKLGWNLNALQFPSGIHLCVTDMHTQP-GVADKFIADVRSC------TAE 499
             |||..| .||...|.::...||      .:|..| .|.|::|  :|.|      |||
  Fly   410 CFRLKGS-DKLNEKLLSIINESG------KLHMVPASVGDRYI--IRFCAVAQNATAE 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sply	NP_652032.1	DOPA_deC_like	132..494	CDD:99743	76/429 (18%)
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:395219	69/427 (16%)